00 Alzheimer's Disease Flashcards Preview

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Flashcards in 00 Alzheimer's Disease Deck (18):
1

What are the two medication classes used for Alzheimer's Disease?

Acetylcholinesterase Inhibitors (prolong ACh activity). NMDA antagonists

2

What medication class should people with AD avoid?

Anticholinergics (worsen memory impairment)

3

What is the generic name of Aricept?

Donepezil (Acetylcholinesterase Inhibitor)

4

What are the ADRs seen with Aricept (Donepezil)?

N/V/D, Bradycardia

5

Which Acetylcholinesterase Inhibitor comes with an ODT option?

Aricept (Donepezil)

6

What is the generic name of Razadyne?

Galantamine (Acetylcholinesterase Inhibitor)

7

What is the generic name of Exelon?

Rivastigmine (Acetylcholinesterase Inhibitor)

8

What is the generic name of Namenda?

Memantine (NMDA Receptor Antagonist)

9

What is a class effect of Acetylcholinesterase Inhibitor's?

N/V/D, Bradycardia

10

Which Acetylcholinesterase Inhibitor causes the most N/V?

Exelon (Rivastigmine), has a BOLD warning for N/V --> watch for anorexia, weight loss

11

What are the ADRs seen with Namenda (Memantine)?

Dizziness, HA

12

Why do we generally avoid using Cognex (Tacrine - Acetylcholinesterase Inhibitor)?

Increases LFTs, causes liver damage

13

Which Acetylcholinesterase Inhibitor has little P450 involvement?

Exelon (Rivastigmine)

14

What does NMDA stand for?

N-Methyl-D-Aspartate

15

How is Namenda (Memantine) dosed?

5mg QD x 1 week, 5mg BID x 1 week, 10mg Qam, 5mg Qnoon. Increase to 10mg BID by week 4

16

Which Acetylcholinesterase Inhibitor should be taken on an empty stomach?

Cognex (Tacrine)

17

Which Acetylcholinesterase Inhibitor should be taken with meals?

Razadyne (Galantamine). Exelon (Rivastigmine)

18

Which Acetylcholinesterase Inhibitor's are available as oral solutions?

Razadyne (Galantamine). Exelon (Rivastigmine)