022514 5 Spinal Diseases Flashcards Preview

B&B Exam 1 > 022514 5 Spinal Diseases > Flashcards

Flashcards in 022514 5 Spinal Diseases Deck (17):
1

What are the three types of hereditary spinal cord diseases?

FAH
freidriech's ataxia
adrenomyeloneuropathy
hereditary spastic paraplegia

2

What causes freidriech's ataxia?

triplet repeat of gene for frataxin leading to reduced levels and loss of function of frataxin

3

What causes adrenomyeloneuropathy? What is sometimes present?

abnormal peroxisomal fatty acid beta oxidation leading to accumulation of very long chain fatty acids in oligodendrocytes and schwann cells (dysmyelination). Adrenal insufficiency.

4

What disease is characterized by:
progressive lower extremity weakness
bladder dysfunction
impaired vibration sensation
UMN signs?

hereditary spastic paraplegia (HSP)

5

What type of primary neoplasm is meningeal carcinomatosis?

extramedullary intradural

6

Meningioma and schwanomma are what type of primary neoplasm?

extramedullary extradural

7

What is characteristic of an epidural abscess?

tenderness to percussion on back

8

What is characteristic of syphilis (tabes dorsalis)? (3)

paraparesis and steppage gait
hyporeflexia with babinski signs
impaired proprioception

9

What is characteristic of HIV?

spongiform myelopathy (spongy lesions in spinal cord)

10

What virus is common in tropical areas?

HTLV-1

11

What is characteristic of a B12 deficiency? (2)

antibody to intrinsic factor
megaloblastic anemia

12

What is characteristic of a copper deficiency?

microcytic anemia

13

What artery is commonly occluded during during stent placement or cut during surgery?

artery of adamkiewicz

14

What type of spinal cord disease is spondylosis?

degenerative

15

What causes spondylosis?

narrowing of the vertebral canal due to degenerative disc disease or osteoarthritis (bone spur thickenings)

16

What happens during hyperextension trauma to the neck?

head is thrown backwards, vertebral arches are severed from vertebral column, vertebral column is displaced anteriorly, vertebral arches impinge spinal cord (hangman's fracture)

17

What happens during hyperflexion trauma to the neck?

head is thrown forwards, anterior vertebral column is broken and displaced posteriorly, impinging spinal cord.