Flashcards in 022514 5 Spinal Diseases Deck (17):
What are the three types of hereditary spinal cord diseases?
hereditary spastic paraplegia
What causes freidriech's ataxia?
triplet repeat of gene for frataxin leading to reduced levels and loss of function of frataxin
What causes adrenomyeloneuropathy? What is sometimes present?
abnormal peroxisomal fatty acid beta oxidation leading to accumulation of very long chain fatty acids in oligodendrocytes and schwann cells (dysmyelination). Adrenal insufficiency.
What disease is characterized by:
progressive lower extremity weakness
impaired vibration sensation
hereditary spastic paraplegia (HSP)
What type of primary neoplasm is meningeal carcinomatosis?
Meningioma and schwanomma are what type of primary neoplasm?
What is characteristic of an epidural abscess?
tenderness to percussion on back
What is characteristic of syphilis (tabes dorsalis)? (3)
paraparesis and steppage gait
hyporeflexia with babinski signs
What is characteristic of HIV?
spongiform myelopathy (spongy lesions in spinal cord)
What virus is common in tropical areas?
What is characteristic of a B12 deficiency? (2)
antibody to intrinsic factor
What is characteristic of a copper deficiency?
What artery is commonly occluded during during stent placement or cut during surgery?
artery of adamkiewicz
What type of spinal cord disease is spondylosis?
What causes spondylosis?
narrowing of the vertebral canal due to degenerative disc disease or osteoarthritis (bone spur thickenings)
What happens during hyperextension trauma to the neck?
head is thrown backwards, vertebral arches are severed from vertebral column, vertebral column is displaced anteriorly, vertebral arches impinge spinal cord (hangman's fracture)