06 Basic Transfusion Medicine Flashcards Preview

02 Hematology And Immunology > 06 Basic Transfusion Medicine > Flashcards

Flashcards in 06 Basic Transfusion Medicine Deck (36):
1

Infusion of blood or blood component

Blood transfusion

2

In a single donation, you can get four components

Packed red blood cell
Platelets
Fresh frozen plasma
Cryoprecipitate

3

Produced by centrifugation leaving the packed RBC in the original bag

Platelet-rich plasma

4

Produced by centrifuging the PRP, removing the platelet-poor plasma

Platelet concentrates

5

Deficient in active platelets and labeled clotting factors
Usually used for rapid and active bleeding only

Whole blood

6

Volume whole blood

450 mL

7

Storage: whole blood

2-6 deg C for 35 days

8

Cellular products after plasma removal by centrifugation or sedimentation

Red blood cells

9

Volume: red blood cells

350 mL

10

Storage: red blood cells

2-6 deg C

11

Indication of RBC transfusion

Symptomatic deficiency of oxygen-carrying capacity or tissue hypoxia due to an inadequate circulating red cell mass

12

Contraindication of RBC transfusion

To treat anemia that can be corrected with non-infusion therapy
A source of blood volume

13

Platelets prepare within _____ post donation

6 hours

14

Volume platelets

60 mL

15

Storage: platelets

22-24 deg C with gentle agitation

16

Indication for platelet transfusion

To treat bleeding due to critically decreased circulating platelet counts or functionally abnormal platelets
Prophylaxis against bleeding at prespecified low platelet counts

17

Contraindication for platelet transfusion

Px with autoimmune thrombocytopenia or thrombotic thrombocytopenic purpura

18

Prepared within 8 hours post donation
Contains all coagulation factors

Fresh frozen plasma

19

Volume: fresh frozen plasma

250 mL

20

Storage: fresh frozen plasma

-18 deg C

21

Indication for fresh frozen plasma

Px with coagulation factor deficiencies
Px who are about undergo invasive procedures

22

Contraindication for fresh frozen plasma

Tx of immunodeficiency states
Plasma exchange procedures

23

Cold insoluble portion of plasma after fresh frozen plasma has been thawed
Includes factor VIII, XIII, fibrinogen, fibronectin, ristocetin

Cryoprecipitate

24

Volume: cryoprepitate

30 mL

25

Storage: cryoprepitate

-30 deg C

26

Indication for cryoprepitate

Bleeding associated with fibrinogen deficiencies and factor XIII deficiency
Patients with hemophilia A or vW disease

27

Residual plasma refrozen after removal of cryoprecipitate
FFP without factor VIII

Cryosupernate

28

Indication for cryosupernate transfusion

Hemophilia B with acute hemorrhage or anticipated surgery
Liver disease
Thrombotic thrombocytopenic purpura

29

Three principles of blood product replacement

Deficiency identified
Deficient component replaced
Blood product should be safe

30

Promotes voluntary blood donations to provide adequate supply of safe blood

RA 7719: National Blood Services Act of 1994

31

Potential donor: age

16-65 years old

32

Potential donor: weight

At least 110 lbs

33

Potential donor: pulse rate

60-100 beats per minute

34

Potential donor: BP

120/80

35

Potential donor: hemoglobin

125 g/L

36

An automated blood collection technique where donor or patient is connected to a cell separator equipment
Remove one or more components from patient's blood using cell separation equipment and return the remaining components back

Apheresis