1-1 (8.29.16) Flashcards Preview

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Flashcards in 1-1 (8.29.16) Deck (24):
1

how serum dif from plasma

serum - no clotting factor

2

Hemoglobin (Hb) =

globin chain + heme

3

Hb + C02 =

carb-amino-hb

4

two categories of WBC
-label each as mono/polynuclear

1 granulocyte (poly)
2 agranulocyte (mono)

5

name the cellular elements in blood
-two names for each

1 red cells (erythrocytes)
2 white blood cells (leukocytes)
3 platelets
(thrombocytes)

6

name major proteins in blood

1 albumin
2 globulins
3 fibrinogen

7

hematocrit def

RBC layer

8

buffy coat (thin layer) is composed of

WBC
platelet

9

blood that is centrifuged will separate by weight into layers:

(order them how they are stacked top to bottom)

1) Plasma (50%)
2) Buffy coat/WBC and platelet (1%)
3) RBC/hematocrit (50%)

10

heme =

ring + iron atom

11

function of platelet

promote blood clotting

12

what cells are the ONLY type of WBC to recirculate

lymphocyte

13

def of recirculate

tissue -> return to blood

14

cytokines react with general/specific receptors on target cells

specific

15

"" are very good at secreting PRO inflammatory cytokine

3 examples

macrophage

-TNF
-Interleukin 1
-IL 6

16

phrase with epitope in it

all antigen receptors on a lymphocyte recognize the SAME epitope

17

" : " ratio for lymphocyte and antigen receptor

1:1

18

two main lineages of leukocytes

1 lymphoid
2 myeloid

19

all cytokines share these 2 things

1 react with specific receptors on target
2 have overlapping functions (read: induce, inhibit effects of other cytokines)

20

define an antigen

any molecule that is recognized by BCR or TCR

21

define epitope

small molecular domain of antigen

22

steps of clonal selection

1 antigen is encountered -> lymphocyte is activated
2 lymphocyte proliferates into identical effector cells (specific for one antigen)
3 some become memory cells

23

read: all progeny of one lymphocyte will have the same receptor

-

24

list out the humoral vs cell mediated response

h: B cells make Ab

c: involves dendritic, T cell, effector T cells