10-20 MOD 3

Question 1

Master cell regulator of the immune system

Answer 1

CD4+ helper T cells

Question 2

Active and passive immunity

Answer 2

• Active Immunity is acquired from an immune response via vaccination or environmental exposure. Long lasting but takes days to week after the first exposure to fully develop a response.
• Passive immunity is immunity transferred from another source. Common example is mother to fetus where IgG antibodies are passed on either placenta or breast milk. Passive immunity is short term protection lasting only weeks or months.

Question 3

Type 1 hypersensitivity reactions

Answer 3

IgE mediated reactions that develop quickly union exposure to Antigen

Question 4

Cells involved in type 1 reactions

Answer 4

Mast cells, Basophils , and eosinophils play important role in development of type 1 reactions because they contain chemical mediator histamine

Question 5

Type 2 Hypersensitivity reactions

Answer 5

Also known as cytotoxic hypersensitivity reactions are antibody mediated reactions. Mediated by IgG or IgM antibodies directed against target antigens on specific host cell surfaces or tissue.

Question 6

Autoimmune Disorders

Answer 6

Occurs when the body immune system fails to differentiate self antigens from non self antigens and mounts an immunologic response against host tissue.

Question 7

Self tolerance

Answer 7

Ability to distinguish self from non self is termed self tolerance

Question 8

Autoreactivity

Answer 8

Term that describes an organism acting against its own tissue

Question 9

Anergy

Answer 9

Loss of lymphocyte response to an antigen occurs and causes a lack of cellular and or humoral immunologic response this is called anergy. State of immunologic tolerance to specific antigens.

Question 10

Autoantibodies

Answer 10

The immune system loses its ability to recognize self and produces what is called autoantibodies.