10 - Gynae - Genital Tract Infections - STIs of Vulva and Vagina Flashcards Preview

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Flashcards in 10 - Gynae - Genital Tract Infections - STIs of Vulva and Vagina Deck (8):
1

Chlamydia - how common in developed world? 5-10% of women aged ?-? have been infected.
Usually ? but urethritis and ? may occur.
1' complx = ? infection - which may also be ?
Can cause ? damage -> ? and / or CPP
? used on urine for screening.
Trt with ? or ?

most common STI in dev world
20-30
aSx
discharge
pelvic
silent
tubal
subfertility
PCR
azithromycin or doxy

2

Gonorrhoea - gram ? diplococcus. common esp where? what is also commonly infected? Commonly aSx, but discharge, ?, bartholinitis and ? can occur.
Systemic complx incl ? and acute, usually monoarticular septic ?
Dx from culture of ? swabs
What is on the increase? what drug and route usually required?
Trt and ?? are essential.

-ve
common esp in dev world
pelvis
urethritis
cervicitis
bacteraemia
arthritis
endocervical
ABx resistance
IM ceftriaxone
partner notification

3

Genital Warts - Condylomata Acuminata - caused by ?
-v common, appearance varies from tiny flat ? in ? skin to small ? swellings
- usually ? and may affect ? where certain ? types (16+18) are ass w dev of ?
-trt w topical ? or ? cream (ext warts only)
-for resistant warts what 2 things can be done?
-? recurrence rate
-vaccines vs HPV now given to who?

HPV
patches
vulval
papilliform
multiple
cervix
oncogenic
CIN
podophyllin
imiquimod
electrocautery + cryo
high (25%)
adolescent girls

4

Genital Herpes - Mostly w ? (though type 1 incr implicated - ? ? virus)
-what is worse, primary or secondary infection?
- multiple small ? vesicles and ? around ? - local ?, ? and systemic Sx common
- lies ? but recurs in ?%
- recurring attacks are ? severe and often preceded by ?
-Dx from ? and ? swabs
-? used in severe infection - reduces ? of Sx if started ? in reactivation
-? herpes has high mortality and can be prevented

HSV2
cold sore
primary
painful
ulcers
introitus
lymphadenopathy
dysuria
dormant
75%
less
tingling
Ex and viral swabs
Aciclovir
duration
early
neonatal

5

Syphilis - incidence ? in UK
- 1' syph: ? painless ? ulcer (chancre) - untrt leads to ??
-2' syphilis - dev ? later, often with ?, ?-like Sx, and ? genital/perioral growths
-now, ? of other ? leading to variety of Sx
-Latent syphilis - follows, resolves ?
-1'/2' during ? carries high risk of ? infection.
-3' s now very ?, dev many ? later, affecting any ?
-Trt at any stage with parenteral (IM) ?

incr
solitary
vulval
2' syph
weeks
rash
flu-like
warty
infiltration
organs
spont
preg
congen
rare
years
organ
penicillin

6

Trichomoniasis - T ?. Very prev ? but ? in UK
Typical Sx : ? grey-? discharge, ? irritation, ? dyspareunia but can be ?
-Cervicitis has ? appearance
-Dx from ? ? microscopy, special staining or ? of vaginal swabs
-Trt with ?

vaginalis
worldwide
rare
offensive
green
vulval
sf
aSx
strawberry
wet film
culture
metronidazole

7

HIV - infection with ? causes ? - ? acquired HIV infections has incr and is now more than from ?
Therefore more ? infected.
->70% Dx in UK heterosexually were infected ?, mostly in ??
-RFs - multiple ??, migration from ???, failure to use ??, presence of other ?, ?, sexual contact with high risk ?

retrovirus
AIDS
heterosexually
MSM
women
abroad
subsaharan africa
sex partners
high prev countries
barrier contraception
STIs
IVDU
males

8

HIV - most HIV + women are ?, although seroconversion can be accomp by ?-? Sx with a ?
- What 3 things are diagnostic of AIDS?
- yearly ? done as ? progression to ? is more rapid
-vertical trans to ? prevented by ?, ? caesarian and not ? ?
- with current ART regimes, HIV is increasingly a ? ? condition

aSx
flu like
rash
CD4 <200, dev opportunistic infections or dev malignancy
smear
CIN
malig
fetus
ART
elective
breast feeding
chronic controllable

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