10 Molecules of the Immune System Flashcards Preview

02 Hematology And Immunology > 10 Molecules of the Immune System > Flashcards

Flashcards in 10 Molecules of the Immune System Deck (15):
1

Simplest case
Presence of a functional gene product is dominant over absence of a gene product, or nonfunctional gene product
H and h antigen, Rhesus antigen

One gene, two alleles

2

Describes a trait or disorder in which the phenotype is expressed in those who have inherited only one copy of a particular gene allele

Dominance

3

ABO blood type
Functional is dominant over nonfunctional
Codominance

More than two alleles

4

Two different versions of a gene can be expressed, and each version makes a slightly different protein

Codominance

5

More than three versions of a gene
RhCE gene
Individual only inherits one allele form each parent

Polymorphic gene

6

Deviation that results to abnormal gene expression

Mutation

7

Natural variations in a gene, DNA sequence or chromosome
No adverse effects on the individual
Occurs with fairly high frequency in the general population
HLA-A

Polymorphism

8

A person has more often than one gene for a single set of proteins
HLA class I

Polygeny

9

Polygeny + polymorphism
An individual can be homozygous or heterozygous at each gene

Polygeny and heterozygosity

10

The specific region of an antigen that is recognized by an antibody

Epitope

11

Receptors on membrane

Major histocompatibility complex

12

Killer T cells

MHC class I

13

Helper T cell

MHC class II

14

Have 1 alpha chain and 1 beta chain and three different genes

Class I MHC

15

Dimers of two transmembrane MHC chains

Class II MHCs