10.31 Migraines

Question 1

ER meds

Answer 1

DA antagonists

ketorolac

Question 2

home rescue

Answer 2

ketorolac

Question 3

triptan that’s CI in renal failure and hepatic failure

Answer 3

naratriptan

Question 4

triptan with longest half life

Answer 4

frovatriptan

Question 5

major triptan ADRs

Answer 5

coronary artery vasospasm (5HT1B)

MI

arrhythmia

Question 6

severe drug interactions

Answer 6

eletriptan

Question 7

propranolol increases levels of

Answer 7

rizatriptan

Question 8

triptans CI if also taking MAOIs

Answer 8

sumtriptan

rizatriptan

zolmitriptan

Question 9

ergots

Answer 9

ergotamine

dihydroergotamine

ergotamine plus caffeine

Question 10

ADRs of ergots

Answer 10

hallucinations

vasoconstriction

uterine smooth muscle contraction (CI in pregnancy)

CI in renal failure/impairment

CI in sepsis

Question 11

DA antagonists (antiemetic)

Answer 11

metoclopramide

prochlorperazine

chlorpromazine

Question 12

extrapyramidal sxs of DA antagonists can be prevented using

Answer 12

diphenhydramine

Question 13

H1 antagonist (antiemetic)

Answer 13

promethazine

Question 14

prophylaxis of migraines

Answer 14

anticonvulsants (topiramate, valproate)

beta blockers (propranolol, metoprolol)

CCBs (verapamil)

antidepressants (amitryptiline, venlafaxine)