11c. CV Health - Natural Approach to CVD Flashcards
What is the natural approach to CV health?
Adopt plant-based/Mediterranean diet
Exercise
Stress management
Why is a plant-based/Mediterranean diet beneficial for CV health?
Reduced inflammatory mediators, ROS and RNS
Reduced adiposity
Reduced risk of thrombosis
Increased SCFA production
Improved insulin sensitivity
Increased adiponectin
Improved endothelium function
Why is exercise beneficial for CV health?
Leads to more favourable lipoprotein profile - reduced TG
Improves insulin sensitivity/insulin signalling in vascular endothelium, activating eNOS/increasing NO synthesis
Reduction in BP at rest
Ways to reduce stress to support CV health
Diaphragmatic breathing
Humming/singing to promote PSNS
Herbal teas - chamomile, passionflower, lemon balm
Nutrients to support CV health
C, D, E
O3
Mg
CoQ10
Garlic
Hawthorn
How does vit C support CV health?
Downregulates NADPH oxidase - key source of ROS
Upregulates endothelial NO synthase
Lowers platelet aggregation
Dosage of vit C to support CV health
500-1000mg/3 day
How does vit D support CV health?
Modulates NO synthesis
Modulates RAAS
Lowers BP
Dosage of vit D to support CV health
600-1000iu/day
How does vit E support CV health?
Protects endothelium from ROS (with vit C)
Supports NO synthesis (with vit C)
Reduces oxidation of LDL-C
Inhibits platelet aggregation
Dosage of vit E to support CV health
400-800iu/day
(not with warfarin)
How does O3 support CV health?
Improves lipid and lipoprotein profiles
EPA stabilises cellular membranes
DHA supports membrane fluidity
Dosage of O3 to support CV health
3-6g/day
(not with warfarin)
How does Mg support CV health?
Modulates neuronal excitation, intracardiac conduction and myocardial contraction through regulation of ion transporters
Helps regulate vascular tone
Stabilises heart rhythm
Dosage of Mg to support CV health
500-800mg/day
(glycinate/taurate)
