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Flashcards in 14. Changes in glomerular dynamics Deck (15):
1

effect oof NSAIS on renal function

NSAIDS inhibit prostaglandins ( that preferentially dilated afferent arteriole and increase RPF and GFR , no the FF)
--> constriction of afferent arteriole --> RPF and GFR, not FF---> constriction of afferent arteriole --> decrease of RPF and GFR, not the FF -> IN LOW RENAL BLOOD STATES --> ACUTE RENAL FAILURE

2

effect of ACE inhibitors on renal function

ACE inhibitors decrease angiotensin 2 ( that preferentially constricts efferent arteriole and decrease RPF, increase GFR and increase FF) --> dilation of efferent arteriole --> increase RPF, decreased GFR, so decrease FF )

3

prostaglandins vss angiotensin 2 on renal function

prostaglandins --> preferentally dialted affent arteriole and increase RPF and GFR, not he FF
- angiotensin 2 --> preferentially constricts effernt arteriole and decrease RPF, increase GFR and increase FF

4

Affrent arteriole constriction -
GFR, RPF, FF?

GFR,: decreased
RPF: decreased
FF:-

5

Efferent artetiole constriction
GFR, RPF, FF?

GFR,: increased
RPF: decreased
FF: increased

6

increased plasma protein concentration
GFR, RPF, FF?

GFR,:decreased
RPF:-
FF:decreased

7

decreased plasma protein concentration
GFR, RPF, FF?

GFR,:increased
RPF:-
FF:increased

8

constriction of ureter
GFR, RPF, FF?

GFR,:decreased
RPF:-
FF:decreased

9

dehydration
GFR, RPF, FF?

GFR,:decreased
RPF: decreased
FF: iNCREASED

10

filtration fruction on dehydration

increased

11

• Describe the effects of afferent arteriole constriction on renal plasma flow, glomerular filtration rate, and filtration fraction.

Renal plasma flow decreases; glomerular filtration rate decreases; filtration fraction does not change

12

• Describe the effects of efferent arteriole constriction on renal plasma flow, glomerular filtration rate, and filtration fraction.

Renal plasma flow decreases; glomerular filtration rate increases; filtration fraction increases

13

• Describe the effects of elevated plasma protein concentration on renal plasma flow, glomerular filtration rate, and filtration fraction.

Renal plasma flow does not change; glomerular filtration rate decreases; filtration fraction decreases

14

• Describe the effects of reduced plasma protein concentration on renal plasma flow, glomerular filtration rate, and filtration fraction.

Renal plasma flow does not change; glomerular filtration rate increases; filtration fraction increases

15

• Describe the effects of ureter constriction on renal plasma flow, glomerular filtration rate, and filtration fraction.

Renal plasma flow does not change; glomerular filtration rate decreases; filtration fraction decreases

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