14 - Female Reproductive Disorders Flashcards Preview

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Flashcards in 14 - Female Reproductive Disorders Deck (9):
1

primary amenorrhea definition

delay of menarche beyond age 16, or beyond 13 in absence of 2ndary sex characteristics

2

functional hypothalamic amenorrhea - pathophys and likely causes

reduced GnRH drive > low / borderline low levels of FSH and LH > anovulation

cause - not a pathologic dz. maybe mediated through leptin, assoc w/ hypercortisolemia

3

Sheehan's syndrome

pituitary infarct from postpartum hemorrhage

4

Turner's syndrome - classic findings

primary amenorrhea, short stature, sexual immaturity, webbed neck, short metacarpals, broad chest / widely spaced nipples, droopy eyelids, low hairline, low set ears, short 4th toe, coarctation of aorta

5

Mullerian agenesis

no mullerian structures + renal and bone abnlmalities. genetically female

6

complete androgen insensitivity pts have no mullerian structures as well as what other key exam finding?

decreased body hair

7

Asherman syndrome

intrauterine adhesions that can form an outflow obstruction
usually caused by surgery or curettage

8

hirsutism

excessive androgen dependent hair growth (upper lip, chin, midsternum, upper abdomen, back, buttocks)

9

ddx of hirsutism

r/o malignancy (adrenal or ovarian adenoCA)
cushing's
non classic adrenal hyperplasia
PCOS
drugs - androgens, anabolic steroids, progestins
hyperprolactinemia
idiopathic