15: evolutionary relatedness Flashcards
what is endosymbiosis?
one organism lives inside the other and both benefit
What is an example of an endosymbiotic relationship? What does each gain?
our relationship w the good bac flora in our colon; we get vitamin K and they crowd out potential pathogens; the get food and shelter
What is an example of bacteria in our colon?
E. coli
What happens when the normal flora of the colon is wiped out by antibiotics? What is the name of the pathogen?
the person can develop a colon infection w Clostridium difficle
What are some characteristics of Clostridium difficle?
they form spores; difficult to get rid of bc it is not affected by antibiotics
What happens after the C. difficle spores germinate?
it causes pseudomembranous colitis (inflammation of colon)
What is used to treat C. difficle? what is it? how can it be administered?
fecal transplant; feces from another person in moved into the colon; colonoscopy, enema, or capsule
What does the endosymbiotic theory state?
the mitochondrion developed when a large nucleated cell engulfed an aerobic bacteria
what is a heterotroph?
org that gets its food from complex organic molecules
what is a phototroph?
org that uses light to create its energy source
what is the evidence for the endosymbiotic theory?
basically the bac and mitochondria ribosomes are very similar:
1. both have circular chromosomes
2. both have ribosomes smaller than the euk ones
3. ribosomes in both are resistant to diphtheria toxin and sensitive to streptomycin
What does diphtheria toxin do? How? which ribosomes does it affect?
stops elongation of the peptide during translation by interfering w elongation factor; cytoplasmic (euk)
what does streptomycin cause in cytoplasmic ribosomes?
no effect
What does streptomycin do? in which org?
interferes with initiation of translation= by preventing the binding to the ribosome of the tRNA carrying the 1st amino acid (N-formylmethionine).
What is the first amino acid in bacteria? and Eukarya and Archaea?
N-formylmethionine; methionine