1.5.4 control of programmed cell death Flashcards
how is apoptosis triggered
by cell death signals (external or internal)
what is the production of death signal molecules from lymphocytes an example of
external death signal
what is dna damage an example of
internal death signal
what do external death signal molecules bind to
a surface receptor protein
what does the binding of external death signal molecules to surface receptor proteins trigger
a protein cascade within the cytoplasm
what does an internal death signal resulting from dna damage cause
activation of p53 tumour suppressing protein
what causes the activation of p53 tumour suppressor proteins
an internal death signal resulting from dna damage
what are caspases
types of protease enzyme
which death signal type results in the activatin of caspases
both
what do caspases cause
the destruction of the cell
when is apoptosis essential
during development of an organism to remove cells no longer required as development progresses or during metamorphosis
when may cells initiate apoptosis
in the absence of growth factors
