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Flashcards in 2/15 Weller CNS Infections Deck (83):
1

What casuses meningitis

Bacterial
Viral
Fungal
Protozoan

2

Meningitis Symptoms
3

Fever Headache
Stiif NEck

3

Encephalitis Def

Swelling of Brain

4

ENcephalitis symptoms

Fever Headache
Stiff Neck

5

Encephalitis caused by what?

Mostly Viral
But also others

6

Brain Abscess/subdural Empyema caused by what

Bacterial

7

Purulent Meningitis Def

Acute Infection
Inflammatory Exudate
Often bacterial
If untreated, usually deadly

8

Chronic meningitis Def

Gradual Onset
Can be mycobacterial or fungal
Onset over period of weeks

9

Aseptic Meningitis Def

Increase of cells (plocytosis)
There is absence of bacteria or fungi
Often viral
Inflammation of meninges withour clinical evidence of damage to neural tissue

10

Encephalitis is mostly caused by

Viruses
Could be casues by demyelination

11

CLinically who is diagnosed with meningitis?

PPl with MAY have signs similar to aseptic meningitis but ALSO show CNS dysfunction(like seizures)

12

Meningoencephalitis def

Describes pts with meningeal and encephalitic manifestations

13

4 routes to CNS infection

1) Hematogenous
2) Contguous focus of infection
3) Direct inoculation
4) Nervous system

14

Hematogenous def

Through blood vessels

15

Contiguous focus of infection

Sinus
Ear
Oral cavity

16

Direct innoculation def

Trauma
surgery
Lumbar puncture

17

Nervous system route CNS infection Def

Retrograde movement to brain

18

Hematogenous route infectious agent

Viral
Bacterial
Fungal

19

Contiguous nfectious agent

Bacterial

20

Direct Inoculation Infectios agent

Bacterial

21

Nervous system infectious agent

Viral

22

Focal infection def

Infection at one specific infection

23

COntiguous focus exposure

ANy infection close to CNS that spreads to CNS not by blood nor nervous system

24

What type of infection is it if there s damage in CNS structure and pathogen gets access?

Direct Inoculation

25

Leukocytes in viral infections are ____ than normal

Higher

26

What number are leukocytes in viral infection

80

27

What number are leukocytes in bacterial infection

800

28

What number are leukocytes in Tuberculosis and mycosis

100

29

polymorph number in viral infection

<50

30

Polymorph number in bacterial infection

>60

31

Polymorph number in tuberculosis or mycosis infection

<50

32

Number of glucose in viral infection

>60

33

Number of glucose in bacterial infection

<45

34

Number of glucose in tuberculosis and mycosis

<45

35

Protein in viral nfection

30-80

36

Protein in bacterial infection

>60

37

Protein in tuberculosis and mycoss infection

>60

38

Protein when normal

<30

39

GLucose when normal

>60

40

PMNs when normal

0

41

leukocytes when normal

0-5

42

What is the most common type of meningitis

Viral

43

Treatment for viral meningitis

usually resolves itself

44

Whats more severe, viral or bacterial meningitis

bacterial

45

VIral encephylitis def

swelling of brain parenchyma

46

WHat are the mos common infectious agents associated with acute encephalitis

Viral encephalitis

47

What is the most common cause of viral meningitis

Enteroviruses

48

There is increased incidence of enteroviruses when

Summer and fall

49

Who is most at risk for enteroviruses

Children younger than 15

50

What is the second most common cause of viral meningitis

Herpes simplex viruses

51

What is the most common cause of HSV encephalitis

HSV 1

52

WHat is HSV 2 most common of doing

uncomplicated menngitis

53

What would be suspected f pt had chicken pox and got meningitis

Varicella Zoster Virus meningitis

54

Epstein Barr Virus produce what?

Aseptic meningitis
With or without mono

55

Pts with suspected risk factors for HIV have what menigitis?

HIV meningitis

56

When would meningitis occur in relation to HIV infection>

Following primary infection

57

When should arboviral meningitis be suspected?

WHen there is a cluster of meningitis and encephalitis in a restricted geographic area in summer or fall

58

What is classic clinical presentation of rabies

Fluctuating consciousness
autonomic
seizures
hyperactivity
fever

59

Most common bacterial causes of CNS infection on newborns

Group B Strep
E. COli
Listeria
Klebsiella
Enteric Gram Neg bacteria

60

Most common bacterial causes of CNS infection in infants and children

Strep pneumo
Neisseria meningitis
Haemophilus Influenzae

61

Most common bacterial causes of CNS infection in adults

S. pneumonae
N eisseria Meningitis

62

How is strep pneumo aquired

Aspiration
since its found in normall oropharyngeal flora

63

What is the leading cause of meningitis in neonates?

Strep B

64

Symptoms of E. COli

Very smilar to Strep B

65

H. Influenza cayuses meningitis in children of what ages

Less than 2

66

H. influenzae is a disease that affects?

Only humans

67

Where can H. Influenzae be found

nasopahryngeal flora

68

Neisseria Meningitis is aka

meningococus

69

Neisseria meningitis gram stain

GNC

70

N. Meningitis is a disease affecting

only humans

71

N. Meningitis causes what in ppl

Pyogenic meningitis

72

Meningococcus affects who most often

CHildren
Young Adults

73

What process is used by Listeria Monocytogenes once t invades intestinal mucosa

Bacterimia

74

How is Mycobacterium TB spread to CNS

Hematogenous spread

75

Mycobacterium TB affects who

ppl that have had pulmonary TB

76

Crypto Neo affects mostly

Immunocompromised

77

What produces syphils

spirochetes

78

Syphilis infection to CNs s what infection

Secondary since prmary prob hit genitalia

79

What speciaes causes lyme disease

Borrelia burgdorferi

80

Lyme diseases causes what in people

Meningitis
Chronic encephalopathy

81

Syphilis causes what inppl?

Could be asymptomatic OR
Stages of meningitis

82

Creutzfeldt - Jacob disease is caused by

Prions

83

What are the most important pathogens in immunocompromised pts

1) Enterobacteriaca
2) Anaerobes
3) Staphylococci