Flashcards in 2 - Derm - Skin + Systemic disease - Drug eruption - Erythema multiforme Deck (10):
1
Erythema multiforme
- skin change?
- where?
- common in who?
erythematous target lesions
typically extremities, mucous membranes less commonly (EM major if there is)
more common in younger pts
2
Erythema multiforme
-causes and mgmt
infection - HSV
drugs - penicillin, suphonamides, NSAIDs, allopurinol, anticonvulsants
treat/remove cause
3
SJS - pre- skin changes?
prodrome of fever, weakness, respiratory symptoms
4
SJS - skin changes?
target lesions
red macules>papules>plaqes>darkening blistering crusting
5
SJS - where?
may start on backs of hands/feet>progress proximally
always affects mucosal sites - lips tongue cheeks
6
SJS - causes
infection - HSV
drugs - penicillin, suphonamides, NSAIDS, allopurinol, anticonvulsants
7
Toxic epidermal necrolysis (TEN) what happens and where?
widespread erythema, then necrosis and detachment of epidermis (>30% of body area)
mucosal, respiratory and GI involvement
8
TEN - mortality rate? what increases risk a lot?
~30% mortality
x1000 risk in HIV+
9
TEN - causes
Drugs - penicillin, sulphonamides, NSaids, allopurinol, anticonvulsants
10