2006 Exam Flashcards
When used for the treatment of angina pectoris beta-adrenergic receptor blocking drugs can
A. Reduce the amount of nitroglycerin used by patients with angina pectoris.
B. Reduce the increased cardiac work and oxygen consumption that usually accompanies exercise or stress
C. Produce both A and B.
D. Produce neither A nor B.
C. Produce both A and B.
Dihydropyridine type calcium channel blocking drugs, eg Nifedipine are useful for the treatment of variant angina because they
A. Increase the ability of the myocardium to utilize oxygen.
B. Inhibit coronary artery spasm.
C. Do both A and B.
D. Do neither A nor B
B. Inhibit coronary artery spasm.
Which of the following statements about nitroglycerin (Nitrostat) is false?
A. It can alleviate acute type of angina pectoris.
B. It reduces sympathetic nerve activity to the heart.
C. It produces is anti-anginal effect by primarily decreasing preload resulting in decreased myocardial work and oxygen demand.
D. It can prevent the development of angina if it is taken immediately prior to exercise.
B. It reduces sympathetic nerve activity to the heart.
In patients with heart failure, aldosterone receptor antagonists would likely have which of the following effects on the action of digitalis glycosides
A. Potentiate digitalis glycoside action.
B. Inhibit digitalis glycoside action.
C. Have no effect on digitalis glycoside action.
D. None of the above actions.
B. Inhibit digitalis glycoside action.
Centrally acting antihypertensive drugs
A. Include the altitude adrenergic receptor antagonist clonidine (Catapres).
B. Have several unpleasant side effects.
C. Reduce sympathetic outflow.
D. Are usually reserved for use in patients whose hypertension is not well controlled by other drugs.
E. Have all of the above properties.
E. Have all of the above properties.
Thiazide diuretics reduce blood pressure in hypertensive patients by
A. Simulating the production of renin by the kidney.
B. Reducing peripheral vascular resistance
C. Both A and B
D. Neither A nor B
B. Reducing peripheral vascular resistance
One mechanism of the antihypertensive action of beta 1 adrenergic receptor antagonists is to
A. Directly dilate venous blood vessels B. Inhibit the formation of angiotensin-converting enzyme C. Reduce cardiac output. D. Cause a profound diuresis. E. Cause all of the above.
C. Reduce cardiac output.
What impairs adenosine diphosphate (ADP) mediated platelet activation
A. Low molecular weight heparin B. Alteplase ( Activase) C. Warfarin sodium (Coumadin) D. Aspirin E. Clopidigril (Plavix)
E. Clopidigril (Plavix)
What preferentially activates plasminogen in the thrombus
A. Low molecular weight heparin B. Alteplase ( Activase) C. Warfarin sodium (Coumadin) D. Aspirin E. Clopidigril (Plavix)
B. Alteplase ( Activase)
What can slow sinus rhythm and may cause hypertension
A. Amiodarone (Cordarone)
B. Adenosine (Adenocard)
C. Propafenone (Rythmol)
D. Verapamil (Calan)
D. Verapamil (Calan)
What shortens atrial action potential by activating a potassium channel
A. Amiodarone (Cordarone)
B. Adenosine (Adenocard)
C. Propafenone (Rythmol)
D. Verapamil (Calan)
B. Adenosine (Adenocard)
What is used to treat ventricular arrhythmias and prolongs the refractory period
A. Amiodarone (Cordarone)
B. Adenosine (Adenocard)
C. Propafenone (Rythmol)
D. Verapamil (Calan)
A. Amiodarone (Cordarone)
What can increase pacing thresholds and slow conduction velocity
A. Amiodarone (Cordarone)
B. Adenosine (Adenocard)
C. Propafenone (Rythmol)
D. Verapamil (Calan)
C. Propafenone (Rythmol)
Most drugs used for the treatment of angina pectoris are herapeutically effective because they reduce myocardial work and therefore oxygen demand. True or false?
true
A combination of hydralazine and isosorbide dinitrate can reduce mortality in African-Americans with severe heart failure. True or false?
True
