2009 module exam Flashcards

1
Q

Which muscle is responsible for shrugging off against resistance?

A

Trapezius

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2
Q

Which muscle is used for pushing the trunk up while climbing a tree?

A

Latissmus dorsi

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3
Q

Which movement will be lost when a fracture to the tip of the acromion occur?

A

Flexion

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4
Q

Which nerve is affected for lateral rotation beyond 15 degrees?

A

Axillary nerve

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5
Q

Which is a consequence of rotator cuff muscle injury?

A

Painful arc

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6
Q

Which muscle is used for manual drive screw to wood?

A

Biceps brachii

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7
Q

Which artery is responsible for superficial palmar arch?

A

Ulnar

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8
Q

Which is the most common bone of the hand related to fractures?

A

Scaphoid

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9
Q

Which artery runs laterally to pisiform bone?

A

Ulnar

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10
Q

Which muscle is used for medial rotation of humerus?

A

Subscapularis

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11
Q

Which nerve is formed by medial root?

A

Ulnar nerve

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12
Q

Which of the following causes a claw hand?

A

Damage to inferior brachial plexus

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13
Q

Which nerve forms the lateral cutaneous nerve of forearm?

A

Musculocutaneous

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14
Q

Which nerve damage causes winging of scapula?

A

Long thoracic nerve

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15
Q

Damage to musculocutaneous nerve would cause a loss of?

A

Flexion of forearm

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16
Q

Flexion of the MCP and PIP joints of the ring and little fingers is due to a problem in the…

A

Palmar aponeurosis

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17
Q

Which structure exits from the lesser sciatic foramen?

A

Obturator internus

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18
Q

Which ligament is responsible for preventing overextension of the hip joint?

A

Iliofemoral

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19
Q

What is the main blood supply to the head and neck of the femur bone?

A

Medial circumflex femoral

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20
Q

What is the major flexor of the thigh?

A

Iliopsoas

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21
Q

Which of the following flexes the knee joint?

A

Biceps femoris

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22
Q

What is the main muscle that causes dorsiflexion and inversion of the foot?

A

Tibialis anterior

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23
Q

Which is a part of the knee capsule?

A

Popletius

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24
Q

Patient does flexion of the left knee, then internal rotation,
then abduction, then extension, and you hear crackling sounds. What is the cause of the sounds?

A

Lateral meniscus

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25
Which nerve is found near the biceps femoris and the shaft of the tibia?
Common peroneal nerve
26
Which are responsible for adduction of the toes of the leg?
Plantar interossei
27
Avulsion of the subtalar joint would prevent
Inversion + eversion
28
Which is supplied by medial plantar nerve?
Abductor hallicus
29
Which is a competitive inhibitor for xanthine oxidase?
Allopurinol (we know the LT says it’s a non-competitive inhibitor, but in the net it says that it is competitive in low doses, and there is no other right answer)
30
What is given for induction of labor?
PGE2
31
Which drug is used when acetaminophen is toxic?
Acetylcysteine
32
Which drug is used when RA with peptic ulcer disease?
Celexocib
33
Which drug is mainly for IBD?
Sulfasalazine
34
Which drug reverses the action of methotrexate?
Leucovorin
35
Which drug inhibits dihydroorotate dehydrogenase?
Leflunomide
36
What would happen if Na/K pump is blocked?
Resting membrane potential collapse
37
What causes the unidirectional propagation of AP?
Hyperpolarization in refractory period
38
What is the docking protein in nerve terminal?
Synaptobrevin + syntaxin
39
What is retrieval of vesicle membrane from the nerve | membrane called?
Endocytosis
40
What’s the outcome of giving α-latrotoxin (from black widow spider)?
Ca independent exocytosis
41
What is the likely cause of decreased muscle contraction/twitch?
Decreased Ca at muscle fibers
42
What’s responsible for the initiation of ATP-dependent power stroke movement between actin and myosin?
Myosin-head
43
What causes maximum contraction of muscles?
Complete overlap between actin and myosin
44
Unstimulated muscle is stretched by a tool from both sides
Increased passive tension
45
Muscle continuous stimulation of 80 Hz
Induction of tetanization
46
High energy for short periods is modulated by
Creatine phosphate
47
Allosteric activator of glycolysis and glyconeolysis
AMP
48
What is the regulator of fatty acid in aerobic metabolism?
AMP-Activated Kinase
49
Which cell is responsible for bone resorption?
Osteoclasts
50
Which disease is caused by a mutation to FGFR3?
Achondroplasia
51
Which disease is caused by a mutation to SQSTM1?
Paget’s disease | The SQSTM1, TNFRSF11A, and TNFRSF11B genes are involved in bone remodeling
52
Which disease is caused by 1α-hydroxylase?
Rickets
53
Most common cause of septic arthritis?
S. Aureus
54
7-year-old patient with osteomyelitis and sickle cell anemia?
Salmonella typhi
55
Treatment of osteomyelitis caused by salmonella?
Ciprofloxacin
56
Treatment of multi-drug resistant S.Aureus?
Vancomysin
57
45-year-old patient with arthritis and bright red cheeks. Fluid analysis revealed the presence of viral DNA. Whats the causative agent?
Parvovirus B19
58
35-year-old patient with arthritis after traveling to a tropical country and getting bit by a mosquito
Dengue virus
59
Joint aspiration for a patient with osteomyelitis revealed intracellular budding yeast. What is the condition?
Histoplasmosis
60
Which is linked with both onset and intensity of pain?
Catastrophizing
61
Materials used in bone scan are more likely to behave similarly to
Phosphate
62
What is the common antigen that the antibody is directed to in RA?
IgG
63
How are immune complexes normally cleared from our body?
Complement
64
Patient with arthritis was diagnosed with parvovirus B19. | What’s the most likely outcome?
Disease will be self-limited within three weeks
65
42-year-old female with morning stiffness for one hour. T=37.5 and pressure is 140/90 with synovitis. What’s useful in diagnosis?
C-Reactive Protein
66
A patient with Rheumatoid Arthritis was seen to have subcutaneous nodules over his elbow. If we microscopically look at them, what will we found?
Granuloma
67
Patient with fever and chills was diagnosed with synovitis. What is the initial diagnostic approach to the patient?
Joint fluid analysis
68
55-year-old female who is on estrogen supplement therapy (EST) was diagnosed with SLE. What is your advice to her EST?
You should stop taking it to prevent lupus flares
69
Patients with SLE are characterized by
Production of anti-leukocyte antibodies
70
You can mainly differentiate between SLE and RA by the | presence of
Anti-double stranded DNA Antibody | anti-dsDNA antibody test is very specific for SLE
71
What’s meant by “all mtDNA are identical in a healthy individual at birth”?
Homoplasmy
72
Patient with lactic acidosis, hearing loss, and stroke is caused by
Mutation to mitochondrial tRNA
73
Mitochondrial diseases mainly affect the
Muscles
74
What is a special characteristic of collagen?
Triple helix
75
Which is the most frequent amino acid in collagen?
Glycine
76
Which of the following would lead to decreased uric acid | solubility?
Low pH
77
What is the molecule found in crystals in gout patients?
Monosodium Urate
78
How many of these has increased mortality? a. RA b. SLE c. OA
RA=YES OA=NO SLE=YES!
79
A 60-year-old male in casualty for 2 days and pain and effusion in his first MTP joint. It started 3 months ago with recurrent episodes since that time. Physical examination revealed redness and swelling with tophi formation in the 1st MTP joint. What’s the diagnosis?
Gout
80
Why is it hard to study the epidemiology of OA?
No correlation between radiological and clinical | manifestations
81
Patient with an injury to the C6-C7 zygopophyseal joint. What will be affected?
Spinal nerves
82
What innervates the superficial intrinsic muscles at the back?
Posterior rami of spinal nerves
83
Which muscle is most commonly torn in the back?
Erector spinae
84
Which muscle is the major flexor of the vertebra?
Psoas major
85
What is the most common cause of low back pain?
Muscle strain
86
Which part gives the myotome?
Paraxial
87
Failure of fusion of vertebral arches causes
Spina bifida
88
Failure of one half of the vertebral centrum to ossify causes
Scoliosis
89
Which is a common malignant tumor that contains bone matrix | producing cells?
Osteosarcoma
90
Patient with swelling at right knee. Radiological studies showed “soap bubbles” and lesion composed of large osteoclastic cells. What's the diagnosis?
Giant cell tumor
91
Patient with bony lesion associated with translocation (11:22) and glygocen deposition
Ewing sarcoma
92
What is a characteristic of back pain?
It affects mostly people of working ages
93
Alveolar extremities examination revealed loss of sensation on the lateral 5th finger of the foot. Which nerve roots are affected?
L5-S1
94
Patients with intervertebral disk herniation are best diagnosed by
MRI
95
What is the best way to check for supraspinatus tendonitis?
MRI
96
We check X-Ray (lateral side) to see subluxation or whiplash | injury on the...
Cervical vertebra
97
We do MRI to check for the integrity and to find any tear in...
Glenoid labrum