Flashcards in 21. Locations of GI secretory cells Deck (12):
• A patient presents with pallor and macrocytic anemia. She has atrophic gastritis and thus makes antibodies acting at which stomach cells?
Parietal cells (this is pernicious anemia)
• HCl and intrinsic factor are released by ____ cells in the ____ of the stomach.
• A patient who received atropine would have ____ (increased/decreased) production of intrinsic factor.
• ____ is produced by chief cells in the ____ of the stomach.
• Name three types of secretory cells found in the duodenum and their associated products.
I cells (cholecystokinin), K cells (glucose-dependent insulinotropic peptide [GIP], S cells (secretin
• Somatostatin is made by ____ cells in the ____ of the stomach.
• What influence does atropine have on the gastrointestinal secretory cells?
Blocks vagal stimulation of parietal cells only
• A patient is given a dose atropine. Would this decrease acid secretion?
No (the G cells are stimulated by gastrin-releasing peptide)
• Gastrin stimulates the production of which two substances?
Histamine (causes acid secretion) and intrinsic factor
• Name four substances that are secreted directly into the lumen of the stomach
Mucus, pepsinogen, intrinsic factor, and HCl
• Does gastrin stimulate the basal or apical surface of the parietal cells?
Basal surface (gastrin is secreted into circulation to stimulate enterochromaffin-like and parietal cells)