23. Cell surface proteins Flashcards Preview

Immunology > 23. Cell surface proteins > Flashcards

Flashcards in 23. Cell surface proteins Deck (11):
1

• Which cell surface proteins are found on helper T cells?

CD4, CD40 ligand, TCR, CD3, CD28

2

Which cell surface proteins are found on cytotoxic T cells?

CD8, TCR, CD3, CD28, CXCR4/CCR5

3

On T-cell surfaces, ____is associated with the TCR, which binds to____. ____ binds to B7 during antigen-presenting cell signal transduction.


CD3, the antigen-MHC complex; CD28

4


• Which cell surface proteins are found on B cells?


Immunoglobulin (Ig), CD19, CD20, CD21, CD40, major histocompatibility complex (MHC) II, B7

5

Patients with Epstein-Barr virus (EBV) are more likely to have a B-cell lymphoma. How does EBV interact with B cells to make this possible?


On B cells, Epstein-Barr virus binds to CD21 (you can drink Beer at the Bar when you're 21)

6


• Which cell surface proteins are found on macrophages?


Major histocompatibility complex II, B7, CD40, CD14, receptors for Fc and C3b

7

Which cell surface proteins are found on natural killer (NK) cells?


Receptors for major histocompatibility complex I, CD16, CD56

8


• On natural killer (NK) cells, which CD binds the Fc region of immunoglobulin G (IgG)? Which CD is a unique marker for identifying NK cells?


CD16; CD56

9

Do all human cells have major histocompatibility complex I (MHC I)?
n


No, as mature red blood cells do not have MHC I

10


• Which cell surface protein on B cells binds antigen?


Immunoglobulin

11

A woman receives a bone marrow transplant. Afterwards, detection of which cell surface protein indicates a successful procedure?


CD34 (indicative of hematopoietic stem cells)