23. Diabetes Flashcards Preview

EXB 112 FINAL > 23. Diabetes > Flashcards

Flashcards in 23. Diabetes Deck (17):
1

What is diabetes mellitus?

Chronically elevated blood glucose

2

What is a normal level of fasting blood glucose?

3

What range of fasting blood glucose characterizes pre-diabetes (impaired glucose tolerance)?

110-125

4

What range of fasting blood glucose characterizes diabetes mellitus?

> 125

5

What characterizes type I diabetes?

-Low, no insulin
-Auto-immune destruction of insulin-making cells
-Not a hypokinetic disease (not related to inactivity or accumulation of body fat)

6

What % of diabetes cases are type I?

10%

7

What % of diabetes are type II?

> 90%

8

When is the onset of type II diabetes?

Mid-life

9

What is the criteria of the metabolic syndrome?

-Abdominal obesity (BMI > 25; waist circum > 35 in for females or > 40 in for males)
-Hyperlipidemia (esp. low HDL, high triglycerides)
-Diabetes
-Hypertension

10

What characterizes type II diabetes?

-Insulin levels are normal or high
-Insulin receptors are insulin resistant
-Highly related to inactivity and excess fat

11

What are the acute, immediate manifestations of hyperglycemia?

-Polyuria (excessive peeing)
-Polydypsia (excessive thirst)
-Polyphagia (excessive eating) and/or spontaneous weight loss

12

Explain diabetic keto-acidosis.

-Elevated blood glucose cannot enter the cells w/o insulin
-Cell must rely on internal energy stores (fat oxidation)
-Final carbon fragments produce acidic ketone bodies

13

What does the ADA recommend after the 1st diagnosis of diabetes?

GXT or other CV screening 10 years after 1st diagnosis

14

What are the short term complications of diabetes?

-Dehydration due to polyuria and polydypsia
-Weight loss and muscle-wasting
-Hypoglycemia (due to Rx)

15

What are the long term complications of diabetes?

-Accelerated atherosclerosis
-Micro-vascular occlusion (retina, kidneys, nerves, extremities)

16

What is the leading cause of death in diabetics?

CVD

17

What is the primary cause of kidney failure and blindness in the U.S.?

Diabetes