Flashcards in 25. Hypothyroidism vs. hyperthyroidism Deck (23):
hypothyroidism - labfinH if qprimary
1. increased TSH ( if primary)
2. decreased fT3 and fT4
hypothyroidism - increased TSH
sensitive lab test for primary hypothyroidism
hypothyroidism - hypercholesterolemia is due to
decreased LDL receptror expression
hyperthyroidism - lab findings
1. decreased TSH ( if primary)
2. increased fT3 and fT4
sensitive lab test for primary hyperthyroidism
hyperthyroidism - hypocholesterolemia is due to
increased LDL expression
hyperthyroidism - clinical symptoms and signs
1. heat intolerance
2. weight loss with increased appetite
3. hyperactivity, anxiety , insomnia , tremor
5. increased reflex
6. warm moist skin
7. fine hair
8. chest pain, palpitations, arrhythmia
9. pretibial myxedema ( Graves ), periorbital edema
10 thyrotoxic myopathy ( proximal muscle weakness with normal CK)
hyperthyroidism - heat intolerance is due to
increased heat production hy
hyperthyroidism - heart symptoms
chest pain, palpitations, arrhythmia
hyperthyroidism - chest pain, palpitations, arrhythmia are due to
increased number and sensitivity of β-adrenergic receptors
hypothyroidism - clinical symptoms and signs
1. cold intolerance 2. weight gain with decreased apepetite 3. constipation 4. decreased reflex
5. Myxedema ( facial / periorbital ) 6. bradycardia, dyspnea on exertion 7. Hyporeactivity, lethargy , fatigue , weakness 8. dry, cool skin, coarse brittle hair
9. hypothyroid myopathy ( proximal muscle weakness with increased CK )
hypothyroidism - heart symptoms
bradycardia, dyspnea on exertion
hypothyroidism vs hyperthyroidism - hair
hypothyroidism : coarse brittle hair
hyperthyroidism : fine hair
hypothyroidism vs hyperthyroidism - skin
hypothyroidism : dry cool skin
hyperthyroidism : warm moist skin
Your patient states that she has been constipated, cold, and gaining weight despite decreased appetite. What is the most likely diagnosis?
A postmenopausal female has heat intolerance, weight loss, palpitations, and diarrhea. What lab findings do you expect to see?
Low thyroid-stimulating hormone (if primary disease), and high free or total T3/T4 (she likely has hyperthyroidism)
A woman has weight gain, lethargy, cool dry skin, and brittle hair; she exhibits hyporeflexia on exam. What lab findings do you expect?
Increased thyroid-stimulating hormone (sensitive for primary disease) and low free T4 (she likely has hypothyroidism)
What cardiac symptoms can hyperthyroidism cause? What can hypothyroidism cause?
Hyperthyroid: chest pain, palpitations, arrhythmia from increased β-adrenergic receptors; hypothyroid: bradycardia, dyspnea on exertion
A patient with a known thyroid condition is lethargic, with swelling in the face and periorbital region. Diagnosis?
Myxedema resulting from hypothyroidism
A patient with a known thyroid condition is hyperactive, with hyperreflexia, and has swelling on her shins. Diagnosis?
Pretibial myxedema due to Graves disease (hyperthyroidism)
How do hypo- and hyperthyroidism each affect the skin? The hair?
Hypothyroidism causes dry, cool skin and coarse, brittle hair, whereas hyperthyroidism causes warm, moist skin and fine hair