26. Peyer patches Flashcards Preview

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Flashcards in 26. Peyer patches Deck (11):
1

Peyer patches defintion

Unencapsulated lymphoid tissue A found in
lamina propria and submucosa of ileum.

2

Peyer patches Contain

specialized M cells that sample and
present antigens to immune cells.

3

B cells stimulated in germinal centers of Peyer
patches differentiate into

IgA-secreting plasma
cells,

4

IgA-secreting plasma
cells, which ultimately reside in

lamina
propria.

5

IgA

receives protective secretory
component and is then transported across the
epithelium to the gut to deal with intraluminal
antigen.

6

• Peyer patches are made of which type of tissue: mucosal, lymphoid, or muscularis?

Lymphoid (Peyer patches are made of unencapsulated lymphoid tissue)

7

• In what two layers of the gastrointestinal tract are Peyer patches found?

The lamina propria and the submucosa

8

• What is the main action of M cells?

M cells take up antigens from the gut lumen for presentation to B cells and eventual creation of immunoglobulin A (IgA) antibodies

9

• After stimulated B cells from Peyer patches have differentiated into plasma cells, what do they then secrete?

Immunoglobulin A, or IgA (Intragut Antibody)

10

• After being secreted, immunoglobulin A (IgA) functions to bind what?

Intraluminal antigens (think IgA, the Intragut Antibody

11

• What must IgA receive before it can be transported through the epithelium and into the gut to deal with antigens?

Protective secretory component

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