Flashcards in 27. Bile Deck (9)
bile salts (bile acids conjugated to glycine or taurine, making them water soluble),
phospholipids, cholesterol, bilirubin, water, and ions. catalyzes
Digestion and absorption of lipids and fat-soluble vitamins
Cholesterol excretion (body’s only means of eliminating cholesterol)
Antimicrobial activity (via membrane disruption)
rate‑limiting step of bile acid synthesis -catalyst
• What are the six components of bile?
Bile salts, phospholipids, cholesterol, bilirubin, water, and ions
• What is the only means of cholesterol excretion from the body?
• Bile acid conjugation makes bile _____ (more/less) soluble by biding to which two amino acids?
More, glycine and taurine
• In a patient who is unable to produce bile, what physiologic functions would be impaired?
Excretion of cholesterol, digestion and uptake of lipids and fat-soluble vitamins, & antimicrobial activity
• A patient has defective cholesterol 7&945;-hydroxylase activity. Does this affect his ability to absorb vitamins in any way?
Yes, as this impairs the rate-limiting step of bile synthesis (one of bile's functions is to assist with vitamin digestion and absorption)