3-1 (8.31.16) Flashcards Preview

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Flashcards in 3-1 (8.31.16) Deck (42):
1

artery is made of what tunica

media

2

which is bigger: elastic or muscular artery

elastic

3

does arteriole have elastic lamina

no

4

veins have very
-little
-a lot
of muscle

little

5

adventita is thicker on
-artery
-vein

media is thicker on
-artery
-vein

adv-VEIN

media-artery

6

"" have valves

veins (NOT arteries)

7

neurovascular bundle consists of

-artery
-vein
-nerve

8

precapillary sphincters control what

when closed, blood doesn't go where

blood flow bt arteriole and cap

cap bed

9

describe cap layers (tunica)

only endothelial

10

read: innate has to happen BEFORE adaptive happens

n

11

read: phagosome fuses with lysosome to generate phagolysosome, where microbes are eliminated

-

12

what process provides a physical barrier to prevent the spread of infection

inflammation

13

define extravasation

recruitment of leukocytes into infected tissue

14

Lymphatic system function

-return tissue interstitial fluid TO blood
-filter blood and lymph

15

T cell origination story

originate in BM
differentiate in thymus

16

define secondary lymphoid organ

where B and T RESIDE
-where lymph is filtered

17

list out 3 examples of secondary lymphoid organs

lymph node
spleen
tonsil

18

cellular immunity is mediated by B/T cells

T

B cell - humoral immunity

19

T cell vs B cell %

T: 80% of lymphocytes

20

other than dendritic, what can serve as APC

macrophage

21

bone marrow cellularity (increases/decreases) with age

what replaces active hematopoietic elements

decreases

adipose

22

thymus of an adult is (bigger/smaller) than that of a child's

smaller

23

what cells are found in the thymus?

-T
-macrophage
-stromal epithelial

24

def thymocyte

def the process they go thru to be selected

precursor T cell

less than 5% will make it thru the process (aka survive to leave)

25

is lymph filtered in thymus

therefore...

no

there are no afferent lymphatics

26

thymus location

mediastinum in chest

27

which type of cell in lymphatic system is ONLY found in thymus

epithelial reticular cell

28

does the thymus have afferent lymphatics

NO

29

COP vs clathrin

COP: ER to Golgi; within Golgi

clathrin: Golgi to cell surface or to endosomes

30

afferent -> efferent lymphatics (what's in bt)

STM sinuses

31

unencapsulated lymphatic tissue refers to what category

lymphoid follicles found in CT of other organs

32

name the ONLY lymphoid organ with stratified squamous as its epi

tonsil

33

which organ has crypts

tonsil

34

have only efferent lymph vessels

why

Tonsil
thymus

nothing is filtered in it

35

which of the ALTs are partially encapsulated

tonsil

36

MALT appearance (one word)

follicle

37

which complement pathways are immediate (there is more than one)

which is the fastest
why

lectin
alternative

alternative
C3 spontaneously hydrolyzes

38

name the main effector molecule in complement system

C3b

39

what does C3b exactly do?

it is deposited on a microbe THEN it can make three things happen
1) cause inflammation with C5a or C3a
2) bind to phagocyte C3bR (opsonization) so that phagocytosis occurs
3) form the MAC, which leads to lysis of microbe

40

dif bt primary and secondary lymphoid organ

1-lymphocytes differentiate
2-L are activated by antigen in these organs

41

name all antigen presenting cells

-Dend
-macrophage
-B cell

42

what type of collagen forms the Hassall's corpuscle

-know where Hassall's corpscule is located in the first place

epithelial reticular

thymus