3 - Paeds - Gastro - Malabsorption + Parasitic Infections Flashcards Preview

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Flashcards in 3 - Paeds - Gastro - Malabsorption + Parasitic Infections Deck (11):
1

6 general causes for malabsorption

-cholestatic liver disease/biliary atresia
-lymphatic leakage of obstruction
-short bowel syndrome
-loss of terminal ileal function
-small intestinal mucosal disease
-exocrine pancreatic dysfunction eg CF

2

Why would
-lymphatic leakage or obstruction
-exocrine panc dysfx
cause malabsorption?

-lymph - chylomicrons (carry absorbed lipids) unable to reach thoracic duct and circulation
-panc - absent lipase proteases and amylase > defective digestion of TGs, protein, starch

3

what specific malnutrition would you see in loss of terminal ileal function? why may this occur?

absent bile acid and vitamin B12 absorption
Crohns or resection

4

Sx of malabsorption?

abnormal stools - difficult to flush and stinks the whole house out
FTT/poor growth
specific nutrient deficiency

5

Ix?

dietician review
stool samples
urinalysis
bloods
endoscopy
biopsy

6

what are you looking for in stool? what about urinalysis?

stool - pH, bile acids, large proteins, parasites
urinalysis - evidence of infection, transporter dysfunction

7

Why are children vulnerable to picking up parasites? 3 commonest parasites?

poor hygiene and time on floor
worms, giardia lamblia, cryptosporidium

8

Worms - most common in who? Sx? treatment?

most common in kids
usually aSx - may give itchy anus/vagina, disturbs sleep
trt whole house - good hygiene and medication (mebendazole or piperazine)

9

Giardia Lamblia - more common where/who? transmission? main source?

reduced immunity, poor sanitation, endemic areas
faecal-oral trans, main source = contaminated water

10

Giardia Lamblia - Ix? Sx?

stool microscopy to Ix
Sx - travellers diarrhoea (>10d), wt loss, FTT, nausea, abdo pain, anorexia

11

Cryptosporidium - common in kids with.. ? source? Sx?

with AIDS
contamination from animals -> livestock, petting zoos, nursery, food, water
sx - low grade fever, malaise, sudden onset watery diarrhoea ~2wks

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