30. Achalasia Flashcards Preview

Gastrointestinal > 30. Achalasia > Flashcards

Flashcards in 30. Achalasia Deck (11):
1

mechanism

failure of relaxation of lower esophageal sphincter ( LES) due to loss of myenteric ( Auerbach ) plexus --> high LES resting pressure and uncoordinated or absent peristalsis

2

clinical presentation

1. progressive dysphagia to solids and LIQUIDS ( vs obstruction - solids only )
2. putrid breath

3

image

Bird's beak --> barium swallow shows dilated wsophagus an area of distal stenosis

4

complication s

associated with increased risk of esophageal ca ( both SCC and adeno, but esp SCC

5

causes of achalasia

1. idiopathic
2. Chagas disease T.cruzi - kissing bug)
3. extraesophageal malignancy ( mass effect or paraneoplastic)

6

• Achalasia results from the failure of what process to occur?


Relaxation of the lower esophageal sphincter

7

• In a man with high lower esophageal sphincter resting pressure/uncoordinated peristalsis, you see innervation loss from which plexus?

The myenteric (Auerbach) plexus, which innervates the LES

8

• What is the most common presenting symptom of achalasia?

Progressive dysphagia to both solids and liquids (vs. obstruction, which presents as dysphagia to solids only)

9

• After you diagnose a man with achalasia, you should advise him that he has increased risk for what malignancy?

Esophageal squamous cell carcinoma

10

• A man is diagnosed with new achalasia. He recently traveled to South America. What parasitic disease did he likely contract while there?

Chagas disease (associated with secondary achalasia)

11

• What is the etymology of the word achalasia?

A = absence of, and chalasia = relaxation

Decks in Gastrointestinal Class (88):