30 Renal Physiology Flashcards Preview

2 Pharm Unit > 30 Renal Physiology > Flashcards

Flashcards in 30 Renal Physiology Deck (24):
1

What is the basic functional unit of the kidney?

nephron

2

What does the loop of Henle include?

Proximal straight tubule, descending thin limb, ascending thin limb, ascending thick limb, post macular segment

3

what is the equation for single nephron glomerular filtration rate?

SNGFR=Kf ( deltaP - [pi] )

4

T/F: The urine is iso-osmotic with blood in the distal convoluted tubule.

F; it is iso-osmotic in the proximal tubule

5

where does most of the potassium reabsorption take place?

proximal tubule

6

what percentage of Na, H2O, and bicarb is absorbed in the prozimal tubule?

65%

7

what substances are actively secreted into the urine in the proximal tubule?

organic acids and bases

8

what is the driving force for transport in the proximal tubule?

Na/K ATPase in the basolateral membrane

9

Q image thumb

10

For both kidneys, about how much fluid do both kidneys filter out of the blood in a minute? How much urine do they produce in a minute?

120ml/minute filtered out; 1 ml/minute urine

11

what percentage of total body energy does reabsorption in the kidneys require?

7%

12

Specialized epithelial cells at the distal end of the ascending thick limb are called _____.

the macula

13

What does the macula sense?

14

What do the cells of the macula do if they sense that NaCl concentration is too high? what is this process called?

send a signal to the afferent arteriole to redule blood flow; tubuloglomerular feedback

15

T/F: K diuresis is self limiting due to tubuloglomerular feedback

F, Na diuresis

16

is urine, hypo, iso, or hypertonic in the DCT?

hypotonic

17

T/F: the DCT transports both wather and NaCl

18

which area of the nephron is the diluting segment?

DCT

19

Where does urea leave the nepron?

distal collecting duct only

20

what is a diuretic?

drug that increases solute

21

what is an aquaretic?

something that increases excretion of water but not of solutes (dilutes urine)

22

what is a natriuretic?

23

what is a saluretic?

something that increases the excretion of NaCl

24

What is a Kaliuretic?

something that increases excretion of potassium