32. Autoantibodies Flashcards Preview

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Flashcards in 32. Autoantibodies Deck (32):
1

Anti- Ach receptro

Myasthenia gravis

2

Antibasement membrane

Goodpasture

3

Anti-caridolipin , lupus anticoagulant

SlE, antiphosphoolipid syndrome

4

Anticentromere

Limited scleroderma ( Crest syndrome

5

Antidesmoglein ( antidesmosome

Pemphigus vulgaris

6

Anti-dsDna

SLE

7

Anti-smith

SLE

8

Anti - glutamic acid decarboxylase ( GAD-65)

DM I

9

Antihemidesmosome

Bullous pemphigoid

10

Anti-histone

Drug-induced lupus

11

Anti-Jo-1

Polyomyositis, dermatomyositis

12

anti-SRP

Polyomyositis, dermatomyositis

13

anti-Mi-2

Polyomyositis, dermatomyositis

14

Antimicrosomal

Hashimoto thyroiditis

15

Antithyroglobulin

Hashimoto thyroiditis

16

Antimitochrondrial

primary biliary cirrosis

17

Antinuclear (ANA)

sle not specifici

18

Antiparetial cell

pernicious anemia

19

Antiphospholiapse A2 receptro

primary membranous nephropathy

20

Anti-Scl-70( anti -DNA topoisomerase I)

Scleroderma (diffuese

21

Anti-smooth muscle

Autoimmune hepatitits type 1

22

Anti - SSA, anti -SSB ( anti-Ro, ANti -La)

Sjogren syndrome

23

Anti-TSH receptor

Graves disease

24

Anti-U1 RNP (ribonucleoprotein-Eaton syndrome

Mixed connective tissue disease

25

Voltage-gated calcium channel antibodies

Lambert

26

IgA anti-endomysial

Celiac disase

27

IgA anti -tissue transglutamisase

Celiac disase

28

MPO-ANCA /p-ANCA

Microscopic polyangitis, eosinophilic granulomatosis with polyangiitis ( churg-strauss syndrome

29

PR-ANCA/ c-Anca

Granulomatosis with polyangiitis (wegner

30

Rherumatoid factor

IgM antibody targets IgG Fc region, RA

31

Anti-CCP

RA more specific

32

anti- β2 glycoprotein antibodies -disease

antiphosholipid syndrome