32. Pituitary adenoma Flashcards Preview

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Flashcards in 32. Pituitary adenoma Deck (12):
1

most commonly / arises from

prolactinoma

2

prolactinoma - benign or malignant

benign

3

pituitary adenoma - divide to

1. functional adenoma ( hotmone producing)
2. nonfunctioning adenoma ( silent )

4

nonfunctionaing pituitary adenoma present with

mass effect :
1. bitemporal hemianopia
2. hypopituitarism
3. headache

5

pituitary functional tumor presentation is based on

the hormone produced

6

prolactinoma - symptoms

1. amenorrhea
2. galactorrhea
3. low libido
4. inferitlity
5. osteoporosis

7

treatment of prolactinoma

1. dopamine agonists ( bromocriptine or carbeholide)
2. trannphenoidal resection

8

dopamine agonists for treatment prolactinoma - drugs

1. bromocriptine
2. cabergolide

9

• A 36-year-old woman has bitemporal visual field defects and headache. What is the most likely diagnosis?

Pituitary adenoma, most commonly a prolactinoma, which compresses the optic chiasm, causing a bitemporal hemianopsia

10

• A 36-year-old nonpregnant woman has amenorrhea, low libido, and white discharge from her nipples. How do you treat?

Prolactinoma is treated with dopamine agonists (such as bromocriptine or cabergoline) to shrink the tumor, or transsphenoidal resection

11

• A 25-year-old woman has had trouble getting pregnant and now complains of peripheral vision loss. What is the cause of her infertility?

She likely has a prolactinoma (decreased GnRH, amenorrhea, infertility

12

• A 35-year-old man has bitemporal visual field defects and finds that his shoes don't fit anymore. What lab abnormality will be seen?

High growth hormone, secreted by a somatotropic pituitary adenoma and resulting in acromegaly