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Flashcards in 3.71 Deck (10)
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1
Q

The Rh blood group system is more complex than ABO and is the second most important blood grounp system in terms of ________ medicine because of its high ________

A

transfusion, Immunogenicity

2
Q

How many Rh antigens are there, and how many are common

A

about 50 antigens, only 5 are common

3
Q

what type of Blood is truly a universal doner

A

O-

4
Q

what the three other blood grouping systems mentioned in lecture

A

-Kell (K, can be + or -)
-Duffy (Fy, can Fya and Fyb and + or -)
Lewis (a and b plus + or -)

5
Q

what are the 5 different components of blood that can be donated

A
  • red cells
  • white cells
  • platelets
  • fresh frozen plasma
  • heat-treated plasma
6
Q

what is the most important aspect of transfusion medicine

A

the avoid transfusion reactions

7
Q

what are the five issues that may arise from bad blood transfusions and what issues arise with each

A
  • Hemolytic -antigen-antibody reaction (may be fatel, and concurent with kidney failure)
  • Non-Hemolytic - damaged blood products that release high levels of cytokines, fever chills
  • Alergic - leads to rashes and itching
  • volume overload - pulmonary edema
  • transfer of bacteria - leading to endotoxemia and septicemia, potentially fatal
8
Q

what are the three main tests designed to ensure that any blood transfused into a recipient is compatible with the donar and will not cause a transfusion reaction

A

blood grouping - ABO and Rh
antibody screen
cross match

9
Q

when can hemolytic disease of a newborn (HDN) occure

A

when the mother is Rh Negative and the Baby is Rh Postive, usually only occurs after the first preganancy

10
Q

what can be given to prevent HDN

A

Rh immune globulin