4 - Drug Abuse Flashcards Preview

Pharmacology 2 > 4 - Drug Abuse > Flashcards

Flashcards in 4 - Drug Abuse Deck (19):
1

Which type of drugs are abused because they produce complete satiation of all drives in the body?

Opioids

2

What are the signs of acute opioid overdose?

  • Fixed, pinpoint pupils (miosis)
  • Depressed respiration
  • Hypotension
  • Shock
  • Slow reflexes
  • Drowsiness
  • Coma

3

What are the signs of cocaine use?

  • Nasal bleeding/necrosis
  • Dilated pupils
  • Hypertension - never give epinephrine within 24 hours
  • Localized gingival recession, bleeding and alveolar bone necrosis in maxillary premolar area

4

What is the mechanism of action of methamphetamine?

  • Triggers cascading release of norepinephrine and dopamine and serotinin when meth enters brain

5

What is formication?

The sensation of insects crawling beneath the skin - "crank bugs"

6

What are the clinical signs of methamphetamine use?

  • Dilated pupils
  • Hypertension/tachycardia
  • Anorexia
  • Increased sweating (diaphoresis)
  • Moodiness
  • Xerostomia
  • Bruxism

7

What does prolonged methamphetamine use lead to?

  • Anxiety
  • Aggressiveness/violent behavior
  • Hallucinations
  • Paranoia
  • Seizures
  • Stroke

8

What are the signs of acute overdose of CNS stimulants?

  • Dilated pupils
  • Hypertension
  • Elevated pulse
  • Cardiac arrhythmias
  • Extreme sweating
  • Hyperthermia
  • Hyperactive behavior
  • Tremors

9

What are the characteristics and signs of nicotine?

  • CNS stimulant
  • Highly addictive (physical & psychological)
  • Increases alertness
  • Muscle relaxation
  • Concentration/memory
  • Decreased appetite

10

What are the harmful effects of nicotine?

  • Irritability
  • Hypertension
  • Increased pulse
  • Induces nausea and vomiting
  • Dizziness
  • Coronary artery disease
  • Lung/oral cancer

11

What are the characteristics of hallucinogens?

  • Powerful CNS stimulants
    • Adverse CNS effects
    • Delusions, panic, paranoia 
  • Sympathomimetics
    • Adverse cardiovascular effects - no epinephrine
    • Dilated pupils
    • Abnormal muscle movement and rigidity

12

What are the oral complications of marijuana?

  • Xerostomia
  • Gingivitis
  • Leukoplakia
  • Hyperkeratinized tissues

13

What is the most frequently abused drug?

Alcohol

14

What's the most abused prescription drug abused by teenagers?

Hydrocodone with acetaminophen

15

What is the drug used to treat alcoholism?

  • disulfiram (Antabuse) - causes vomiting with alcohol

16

What is a red flag drug if a patient directly asks for it?

Roxicet

17

What are used to treat opioid overdose/withdrawal?

  • naloxone (Narcan) - acute narcotic overdose
  • methadone - replaces heroin and gradually withdrawn

18

What is an ADHD drug, that is not an amphetamine?

atomoxetine (Straterra) 

19