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Flashcards in 4] Metabolic Disease Deck (48)
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1

2 main types of dysfunction in endocrine and metabolic disease

Hormonal imbalance
Tumor

2

Some signs and Sx of endocrine and metabolic disease

Muscular weakness
Carpal tunnel syndrome bilateral
Periarthritis
Calcitic tendinitis
Adhesive capsulitis
Mental and vital sign changes

3

Hypo or insufficiency of hormone or hyperactivity

Adrenal gland

4

Screening for endocrine and metabolic disease

Check for nodules in the thyroids

5

Pain would be in the

Joint or muscle

6

Many conditions in endocrine and metabolic disease may cause

Bilateral proximal Sx

7

Red flag

PT is not helping improve

8

Digestive enzymes

Exocrine

9

Insulin and glucagon

Endocrine

10

Type I diabetes

Children – young adults
Insufficient insulin production

11

Type II DM

After 40 years old
Defective insulin

12

Risk factors for type I DM

Family history
Genetics
Geography
Age

13

Risk factors for type II DM

No exercise
Fat
Family Hx
Race
More than 45 years old
HTN
Low HDL
Smoker
Gestational diabetes or more than 9 lb baby

14

Signs and Sx of DM

Polyuria
Polydipsia
Polyphagia
Weight loss
Tired and weak
Blurry vision
Irritable
Recurring skin, gum, bladder other infections
Paraesthesia
Delayed healing

15

Hyperglycemia #s

Fasting more than 126

16

Long term complications of DM

Atherosclerosis
Infection
Neuropathies
Periarthritis and hand stiffness

17

Neural pathway connections to the posterior pituitary gland

Hypothalamus

18

What hormones are in the posterior pituitary gland

ADH
Oxytocin

19

What hormones are in the anterior pituitary gland

HGH
ACTH
TSH
FSH
LH
Prolactin

20

Increased secretion of HGH

Hyperpituitarism

21

Long bones

Gigantism

22

2 parts of adrenal gland

Adrenal cortex and medulla

23

What’s in the adrenal cortex

Mineralocorticoids
Glucocorticoids- cortisol
Sex hormones

24

What’s in the adrenal medulla

Epinephrine and norepinephrine

25

Primary adrenal insufficiency

Addison’s disease

26

Secondary adrenal insufficiency

Decreased ACTH acting on adrenals

27

Primary and secondary insufficiency can cause

Hyperpigmentation
Hypotension
Fatigue
Hypercalcemia
Hypoglycemia
Secondary- myalgia, arthralgia

28

Too much cortisol is

Cushing’s syndrome

29

Characteristics of Cushing’s syndrome

Muscle wasting and weakness
Bone loss (kyphosis)
HTN

30

Appearance of Cushing’s syndrome

Moon face
Buffalo hump
Enlarged abdomen