Flashcards in 4. Pancreas and spleen embryology Deck (14)
Pancreas derived from
pancreases embryology - is divided into ( and function)
Ventral pancreatic buds ---> contribute to uncinate process and main pancreatic duct.
The dorsal pancreatic bud alone --> becomes the body, tail, isthmus, and accessory pancreatic duct.
Both the ventral and dorsal buds contribute to pancreatic head.
Annular pancreas ( mechanism and presentation)
ventral pancreatic bud abnormally encircles 2nd part of duodenum; forms a
ring of pancreatic tissue that may cause duodenal narrowing and nonbilious vomiting.
Pancreas divisum mechanism
ventral and dorsal parts fail to fuse at 8 week
Pancreas divisum - mechanism and symptoms
ventral and dorsal parts fail to fuse at 8 week --> mostly assymptomatic but may cause chronic abdominal pain and / or pancreatitis
Splee arises ...
in mesentery of stomach ( hence is mesodermal) but has foregut supply celiac trunk --> spleen artery
mesntery is a
fold of membranous tissue that arises from posterio wall of the peritoneal cavity and attaches to the interstinal tract
• Is the pancreas derived from the foregut, the midgut, or the hindgut?
• A patient is diagnosed with pancreas divisum, and she asks how this developed. What do you tell her?
Failure of the ventral and dorsal pancreatic buds to fuse during embryologic development
• From which dermal layer does the spleen arise: endoderm, mesoderm, or ectoderm?
• The spleen receives blood from the ____ (foregut/midgut/hindgut) vasculature.
Foregut (specifically, the celiac artery) even though the spleen has a mesodermal origin
• A patient has a malformed accessory pancreatic duct. What pancreatic bud did not form correctly?
Dorsal pancreatic bud
• Ventral pancreatic buds contribute to the formation of these three pancreatic structures.
Pancreatic head, main pancreatic duct, and uncinate process