41. Insulinoma Flashcards Preview

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Flashcards in 41. Insulinoma Deck (11):
1

insulinoma treatment

surgical resection

2

insulinoma is a tumor of .... ---> overproduction of .... ---> ....

- pancreatic β cells
- insulin
-hypoglycemia

3

insulinoma - may see

Whipple triad
1. low bloood glucose
2. symptoms of hypoglycemia ( lethargy, syncompe, diplopia)
3. resolution of symptoms after normalization of glucose levels

4

insulinoma - resolution of symptoms after

normalization of glucose levels

5

symptomatic patients with insulinoma - labs

1. decreased blood glucose
2. increased C-peptide

6

insulinoma vs exogenous insulin use ( lab )

- both decreased blood glucose
- increased C peptide in insulinoma, decreased in exogenous use

7

• A patient presents with lethargy and diplopia followed by syncope. Her blood glucose is low with an elevated C-peptide level. Diagnosis?

Insulinoma

8

• Insulinoma is tumor of the ___ cells of the pancreas.

β Cells

9

• A nurse presents with lethargy, syncope, and diplopia. Serum insulin is high and C-peptide level is low. Does she need surgery?

No—with low C-peptide, her presentation is more consistent with exogenous insulin overdose (or abuse); surgery is reserved for insulinomas

10

• A patient with a pancreatic mass has lethargy, syncope, and diplopia. What is this condition called, and how do you treat it?

Hypoglycemia (seen with insulinomas); surgical resection

11

• Explain the Whipple triad of insulinomas.

Low blood glucose, hypoglycemia symptoms (e.g., lethargy, syncope, diplopia), and resolution of symptoms after glucose normalization