44. Expectorants Flashcards Preview

Respiratory > 44. Expectorants > Flashcards

Flashcards in 44. Expectorants Deck (9):
1

Expectorants - drugs

1. Guaifenesin
2. N-acetylcysteine

2

Guaifenesin - mechanism of action

thins respiratory secretions; does not suppress cough reflex.

3

Guaifenesin - cough relex

does not suppress cough reflex.

4

N-acetylcysteine - mechanism of action

liquefies mucus in COPD patients by disrupting disulfide bonds.

5

N-acetylcysteine can loosen mucus plufs by

disrupting disuldide bonds

6

N-acetylcysteine - used for

1. cystic fibrosis
2. COPD
3. anridote for acetaminphen overdose

7

• How does guaifenesin help a patient with a severe cough productive of sputum?

It thins respiratory secretions, but it does not reduce the cough reflex

8

• A patient with cystic fibrosis is prescribed a medication that would loosen mucous plugs. What is the mechanism of action of this drug?

Disrupts disulfide bonds (N-acetylcysteine is a mucolytic

9

• Which mucolytic is also used as an antidote for acetaminophen overdose?

N-acetylcysteine