Flashcards in 44. Expectorants Deck (9):
Expectorants - drugs
Guaifenesin - mechanism of action
thins respiratory secretions; does not suppress cough reflex.
Guaifenesin - cough relex
does not suppress cough reflex.
N-acetylcysteine - mechanism of action
liquefies mucus in COPD patients by disrupting disulfide bonds.
N-acetylcysteine can loosen mucus plufs by
disrupting disuldide bonds
N-acetylcysteine - used for
1. cystic fibrosis
3. anridote for acetaminphen overdose
• How does guaifenesin help a patient with a severe cough productive of sputum?
It thins respiratory secretions, but it does not reduce the cough reflex
• A patient with cystic fibrosis is prescribed a medication that would loosen mucous plugs. What is the mechanism of action of this drug?
Disrupts disulfide bonds (N-acetylcysteine is a mucolytic