Flashcards in 46. Pseudoephedrine, phenylephrine Deck (8):
mechanism of action
Reduce hyperemia, edema, nasal congestion; open obstructed eustachian tubes. Pseudoephedrine
also illicitly used to make methamphetamine.
Hypertension. Can also cause CNS stimulation/anxiety (pseudoephedrine).
also illicitly used
to make methamphetamine.
α-adrenergic agonistc used as nasal decongestants
• What is the main clinical function of pseudoephedrine and phenylephrine? By what mechanism?
Nasal decongestants via α-adrenergic agonism
• What are the clinical indications for pseudoephedrine and phenylephrine?
Reduce hyperemia, edema, nasal congestion; open obstructed eustachian tubes; and act as stimulant (pseudoephedrine only, used to make meth)