46. Pseudoephedrine, phenylephrine Flashcards Preview

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Flashcards in 46. Pseudoephedrine, phenylephrine Deck (8):
1

mechanism of action

α-adrenergic agonistc

2

use

Reduce hyperemia, edema, nasal congestion; open obstructed eustachian tubes. Pseudoephedrine
also illicitly used to make methamphetamine.

3

toxicity

Hypertension. Can also cause CNS stimulation/anxiety (pseudoephedrine).

4

Pseudoephedrine
also illicitly used

to make methamphetamine.

5

α-adrenergic agonistc used as nasal decongestants

Pseudoephedrine, phenylephrine

6

• What is the main clinical function of pseudoephedrine and phenylephrine? By what mechanism?

Nasal decongestants via α-adrenergic agonism

7

• What are the clinical indications for pseudoephedrine and phenylephrine?

Reduce hyperemia, edema, nasal congestion; open obstructed eustachian tubes; and act as stimulant (pseudoephedrine only, used to make meth)

8

• A patient takes α-adrenergic agonists for nasal congestion. What side effects can be expected?

Can cause hypertension and central nervous system stimulation/anxiety