5 - gastric secretion Flashcards

(64 cards)

1
Q

what is the role of fundus

A

storage

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2
Q

what is the role of the body

A

storage, mucous, secreoin of hcl, secreiona of pepsinogne, secreion of hte intrinsic facros

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3
Q

what is the role of the anturm

A

mixing/grinding
gastrin

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4
Q

what are the cellular composition of gasatic glands

A

surface mucous
paritel cell
cheif cell

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5
Q

what is the fucntio of the gastic pit

A

openign of the gastic glend wher the muocus is secred

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6
Q

what is the cell in gastic pit

A

surface mucous cell

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7
Q

wha tis the role of the chief cell

A

secrete pepsinogens

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8
Q

what is the role of the parietal cells

A

hcl and intrinsic factor secretions

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9
Q

what is the ph of teh stomac

A

less than 2

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10
Q

what acid is in the sotmac

A

hcl

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11
Q

where is the role of hte bichomane choline exchanges

A

exhcnes bicarbone for clodiren,

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12
Q

wher is teh bicarbone made

A

from reacting h20 with c02 from blood

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13
Q

what is the role of teh protm posttium atp ase pum

A

excens potsium into the clel with pronts out to form hcl

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14
Q

how does hte cl leave the cell

A

leaky channels

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15
Q

what happens to the blood ph from hcl realse ;after eating

A

slight increa whihc slowling neutlies out

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16
Q

what chemcial caues protons to be relaed

A

gastrin, histamine, prosaglandins, acetylcholine

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17
Q

what recetor does gastrin atttach to and what doe sit relase

A

cckb to reasle ca

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18
Q

what protein kinase is used to transport calcium

A

pkc

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19
Q

what recpeort is used for histamne and what happens

A

h2 recport, turns atp to camp

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20
Q

what recport is used for aceklty coline and what is relased

A

m3 to relae ca

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21
Q

what isthe role of protsalgindes in gastric acid section

A

to act as a inhibitor for gastric acid as work on ac

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22
Q

what do pritne kinases work on

A

protin potisum pump

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23
Q

what type of histeome is associed with allergy

A

h1

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24
Q

what is the cause of a peptic ulcer

A

nsaids, due to decreisng prostlgy producton
h pylori bacteria

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25
waht type of prinetikes is pka
camp
26
what is treatment for gastic acid desction
hcl inhibtion
27
symptoms of stomac ulcer
buring pina, fatique, heartburn loss of appide, nausea, vomming, loading, burning, weightooss, dull pain
28
what sithre role of alcium carbionate and other carbionate compounds
to reduce hcl
29
what drug clasess inhib hcl secteroin
proton pump inhibirots muscarinic antagonists h2 receptor antagonists
30
h2 receptor antagonis examples
cimestine and ranitidine
31
muscarinic antagons
pirenzepine m3 selectiveq and atropine (genrelly)
32
proton pump inhibitors
omeprazole and lansoprazole
33
effect of heplocpalri
causes isnlfatio in mucosa, and leads to ulcer due to it producing high amoiuntes of nh3 which combines with h+ to produce nh4
34
treatment for ulcer
2 high dose antibioitc an da ppi for 1 week
35
what percent fo peple is the medical treatment for ulcerse effeciv
90%
36
what mechanism control gastic acid secteiorn
neurocine, endocrine adn paracrine
37
wher is gastin relased from
g cells
38
what is teh effect of the vagus nerve in cephalic phase
trigger relaed of ach and g cells to release gastine which work on partilc cells
39
whawt isthe the effect of gasatrin an ach on ecl cells in celpahic phase
release hsitamine
40
cephalic phase
wher ehte body gets in prepearion ot start eating as a result of the smell/taste of food
41
what is the gastric phase
when the food arrives in the stomach
42
what nerve is stimuled by the digestein of food
valgs, relaing ach,
43
what happnes whenn peptides are foundin the stomach
g cells relasee gastrin
44
what do gastic adn ach caues relaed
histomin by ecl cells
45
wath i the inteinal phase
when the food eneter the intes ad sotmac acid is redued
46
waht is reled is ther eis acid in the duodeun
secretin
47
what happesn to gastin secton if secretin ins relaed
it is decreaed
48
what happnes if ther is fat in the duoent
gip is realed decreae gasting stiminum of partial cells
49
what happnes to gastin section if gip is relaed
decreased, decrein ghcl section
50
what are enterogastrones
hormoesn relased in resornes to acid, hypertonic soluntiosn, fatty acids, or monoglcries in the duodenum
51
what is the role of the splannich reflex (enterogatric)
to prevent futher acid buildup in the duodeunm by reducing gastrin secreation
52
how do enterogastornes work
inhibit gastric acid secretion reduce gastic emptying - inhigbitng hte motilty pyloric spinger
53
what are exampes of enteroglas
secretin, cholecystokinin, gip
54
what are pepsingsi ph aciteved at
neutrolpph
55
what are peotons roel
incactie enyes to turn int pepsings at pnurelph
56
when are pepsinges relaed
when ph is less then 3
57
whae are pepsins reacived
when ph is abvoe 3
58
where sit he intreici factor relaed form
pariteial cells
59
what is the role of the gastic mucs
cytoproteive role protens muclas surfce from emchail injury nuertal ph, protences agisn gastic acid corrosion and pepsin digestion
60
wher is gatic mcuus relaed from
srucface epithl cells and mucus neck clels
61
what is main role of gip
slows down the digestion of fats to help maintain blood glucose level by reducing gastrin secretion
62
role of somatatin
shud down acid secrtion by decrasing gasting, and histamine secreaion and inhibits pepsingoen section
63
wher is somataisn secred form
d cells in stoahc
64