5. Innate vs. adaptive immunity Flashcards Preview

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Flashcards in 5. Innate vs. adaptive immunity Deck (10):
1

Innate immunity - example of pumps

LPS - gram -- bacteria
Flagellin - bacteria
ssrna

2

innate vs adaptive immunity according to components

innate immunity --> neutrophils, macrophages, monocytes, dendritic cells, NK cells (lymphoid origin, complement
adaptive immynity--> T+B cells, circulating antibodies

3

innate vs adaptive immunity according to origin

innate immunity --> germline encoded
adaptive immynity--> Variation through VDJ recombination during lymphocytes development

4

innate vs adaptive immunity according to resistance persistence

innate immunity --> resistance persists through generations, does not change within an organism lifetime
adaptive immynity--> microbial resisance not heritable

5

innate vs adaptive immunity according to type of response to pathogens (specificicity

innate immunity --> non specific
adaptive immynity--> highly specific, refined over time

6

innate vs adaptive immunity according to response to pathogens

innate immunity --> rapidly (minutes to hours
adaptive immynity-->develops over long periods, memory responce is faster and more rodust

7

innate vs adaptive immunity according to physical barries

innate immunity --> epithelia tigh juctions , mucus
adaptive immynity-->no

8

innate vs adaptive immunity according to secreted proteins

innate immunity --> Lysoezyme , complement, c reactive protein, defensins
adaptive immynity--> immunoglobbins

9

Innate immunity - key in pathogen recognition

Toll like receptors TLR Q pattern recognition receptors tha recognize pathogen associated molecular patterns (PAMPS)

10

Adaptive immunity - key in pathogen recognition

Memory cells : activated B + T cells --> subsequent exposure to a previously encountered antigen --> stronger , quicker immune response