[5] Microbiology of Selected Bacteria and Viruses Flashcards Preview

[OS 217] Infectious Diseases > [5] Microbiology of Selected Bacteria and Viruses > Flashcards

Flashcards in [5] Microbiology of Selected Bacteria and Viruses Deck (20):
1

Humans are what kind of hosts to Arbovirus?

Accidental Hosts

2

What are the Arboviruses with major impact in the Philippines?

Chikungunya Virus
Dengue Virus

3

Arboviruses with major impact in the Philippines EXCEPT:

A. Chikungunya virus
B. Dengue viruses
C. Japanese B virus
D. Yellow fever virus

C? Not sure.

4

Describe: Flavivirus

+ Sense
ssRNA
11kb

5

Where does replication occur in a Flavivirus

Cytoplasm

6

Vector of Dengue Fever

Aedes aegypti
Aedes albopictus

7

Key pathological feature of dengue hemorrhagic fever

Increased vascular permeability with plasma leakage into interstitial spaces associated with increased levels of vasoactive cytokines

8

When do you take the 1st serum sample in cases of dengue?

When do you take the 2nd sample?

1st: Onset of disease ASAP
2nd: 2-3 weeks after

9

[Treatment]

Dengue Fever

Supportive Treatment

10

[Identify: Leptospira]

Pathogenic Species
Free-living Species

P: Leptospira interrogans

F: Leptospira biflexia

11

How do you make cultures selective for Leptospira?

Addition of neomycin or 5-fluorouracil

12

True of leptospires :

a. Uses long chain fatty acids as source of energy
b. Organic matter for nitrogen source
c. Both
d. Neither

A

Leptospires oxidize long-chain fatty acids as an energy source but use Ammonium salts as a nitrogen source, not organic matter

13

First sample you get from a patient with Leptospirosis

Blood

14

After 7-10 days what sample should you get from a patient with Leptospirosis?

Urine

15

Gold Standard Serologic Test for Leptospira

Microscope Agglutination Test

16

Benefits and Drawbacks of One-point Microcapsule Agglutination Test

B: Simple and quick to use

D: Cannot identify serovars

17

In a LEPTO Dipstick what antibodies are being detected?

IgM Antibodies

18

[Treatment: Leptospirosis]

Mild Leptospirosis

1. Oral Doxycycline
2. Ampicillin
3. Amoxicillin

19

[Treatment: Leptospirosis]

Moderate/Severe Leptospirosis

IV Penicillin/Ampicillin

20

This is an effective prophylaxis for Leptospira interrogans

Doxycycline 200mg