5. systemische Sklerose Flashcards

(28 cards)

1
Q

(SSc)

Einteilung (2)

A
  • diffuse kutane (Dc)
  • limitierte kutane (Lc)
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2
Q

(SSc)

limitierte kutane-: Syndrom

A

CREST-Syndrom

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3
Q

(SSc)

CREST-Syndrom

A

C: Calcinosis cutis

R: Raynaud-Syndrom

E: Ösophageale Hypomotilität

S: Sklerodaktylie

T: Teleangiektasien

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4
Q

(SSc)

Manifestationen (2)

A
  • kutane
  • extrakutane
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5
Q

(SSc)

kutane Manifestationen: Lokalisationen (2)

A
  • Finger
  • Gesicht
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6
Q

(SSc)

Sklerodaktylie: Befunde (2)

A
  • Fingerkruppennekrose
  • Madonnenfinger
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7
Q

(SSc)

Madonnenfinger

A

Finger in fixierter, krallenartiger Beugestellung

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8
Q

(SSc)

extrakutane Manifestationen (3)

A
  1. Gastrointestinaltrakt
  2. Lungen
  3. Nieren
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9
Q

(SSc)

Befund im Gesicht

A

Tabaksbeutelmund

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10
Q

(SSc)

Tabaksbeuteulmund

A

Mikrostomie mit perioraler Hautfältelung

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11
Q

(SSc)

Manifestationen im Gastrointestinaltrakt (2)

A

ösophageale oder intestinale Hypomotilität

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12
Q

(SSc)

Manifestationen in den Lungen (2)

A
  • Lungenfibrose
  • pulmonale Hypertonie
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13
Q

(SSc)

Manifestationen in den Nieren (2)

A
  • Niereninsuffizienz
  • aHT
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14
Q

(SSc)

Labor (2)

A
  • Serumelektrophorese
  • Serologie
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15
Q

(SSc)

Serumelektrophorese: Befund

A

Hypergammaglobulinämie

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16
Q

(SSc)

positive Serologie bei fast allen Fällen

17
Q

(SSc)

ANA

A

antinukleäre AK

18
Q

(SSc)

positive Serologie insb. bei LcSSc

19
Q

(SSc)

ACA

A

antizentromere AK

20
Q

(SSc)

positive Serologie insb. bei DcSSc

21
Q

Anti-Scl-70

A

anti-Topoisomerase I

22
Q

(SSc)

Anti-Scl-70: Prognose

23
Q

(SSc)

Bildgebungen (4)

A
  • Röntgen der Hände
  • CT-/Röntgen-Thorax
  • Ösophagusbreischluck
  • Sonografie
24
Q

(SSc)

Röntgen der Hände: Befund

A

gelenkenahe Akroosteolysen

25
(SSc) radiografischer Befund
Lungenfibrose
26
(SSc) Ösophagusbreischluck: Befund
Glasrohr-Ösophagus
27
(SSc) weiterführende Diagnostik
Biopsie (falls nötig)
28
(SSc) Therapie der Wahl
Glucocorticoide p.o.