Flashcards in 50. Dextromethorphan Deck (11):
mechanism of action
antagonizes NMDA glutamine receptors
synthetic codein analog
antitode to overdose
dextromethorpahn - side effects
Has mild opioid
effect when used in excess. N2.. Mild abuse potential. 3.May cause
serotonin syndrome if combined with other serotonergic agents.
Dextromethorphan combined with serteronergic agents
] Symptoms include high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea. Body temperature can increase to greater than 41.1 °C (106.0 °F). Complications may include seizures and extensive muscle breakdown.
• By what mechanism does dextromethorphan suppress cough?
It antagonizes NMDA glutamate receptors
• A patient with a cough overdoses on an NMDA glutamate receptor antagonist. What drug can be used to treat the overdose?
Naloxone (dextromethorphan can cause opioid-like effects
• Why does dextromethorphan have mild abuse potential?
If used in excess, it has a mild opioid effect