50B FINAL! Flashcards
IgA function
“Secretory” antibody that is present in high concentrations in the secretions of mucous membranes and in the intestinal mucosa
Very low circulating levels
Most responsible for preventing infection in the upper and lower respiratory, GI, GU tract
IgD function
Present in low blood concentrations in conjunction with IgM
IgE function
Variable concentration in blood
Associated with antibody-mediated hypersensitivity reactions
IgG function
75% of circulating antibody population
Heavily expressed on second and subsequent exposures to antigens to provide sustained. long-term immunity against invading microorganisms
IgM function
FIRST antibody formed by a newly sensitized B lymphocyte plasma cell
10-15% of circulating antibody population
5 manifestations of inflammation
redness, warmth, swelling, pain, loss of function
Inflammation leukocytes:
Neutrophil
Macrophage
Monocyte
Eosinophil
Basophil
Antibody-mediated immunity leukocyte:
B-lymphocyte
Plasma cell
Memory cell
Cell- mediated immunity leukocyte:
helper/inducer T-cell
Cytotoxic/cytolytic T-cell
Natural killer cell
WBC count
10,000 MM3
100%
Bands count
500 MM3
5%
Mono count
300 MM3
3%
Lymphs count
2800 MM3
28%
Eosins count
150 MM3
1.5%
Basos count
50 MM3
0.5%
Neutrophil function:
provides protection after invaders, especially bacteria, enter the body
destroy by phagocytosis and enzymatic digestion
Self-tolerance:
Recognizing self v non self which is necessary to prevent healthy body cells from being destroyed along with invaders
Self tolerance is possible because of different proteins present on cell membranes
HLA’s are
found on the surface of all body cells of that person and serve as a universal product code for that person
Antigens are
proteins capable of stimulating an immune response
Source of all blood cells, including most immune system cells
bone marrow which produces immature undifferentiated cells called stem cells
3 processes needed for human protection through immunity
inflammation
antibody mediated immunity
cell mediated immunity
3 examples of inflammation without infection
joint sprain injuries
myocardial infarction
blister formation
Segs count
6200 MM3
62%
Creatinine clearance for men
107-139 ml/min
Creatinine clearance for women
97-107 mL/min
Creatinine clearance test measures
the glomerular filtration rate of kidneys
Primary depression results from
lack of neurotransmitters norepinephrine and serotonin in brain
Secondary depression results from
sudden change in person’s life..illness or loss
Primary clinical manifestation of UTI in older adults is
acute confusion
Stochastic theory
biological theory
based on random events that cause cellular damage that accumulates as organism ages
membranes, nucleic acids and proteins are damaged by free radicals which cause cellular injury and aging
Errors in DNA and RNA synthesis occur with aging (which theory)
Stochastic biological theory
Cells wear out and cannot function with aging (which theory)
Stochastic biological theory
Non-stochastic theory
Biological theory
based on genetically programmed events caused by cellular damage that accelerates aging of the organism
cells divide until they are no longer able to; this triggers apoptosis or cell death (which theory)
Non stochastic biological theory
Cells have a genetic programmed aging code (Which theory)
Non-Stochastic Biological Theory
Problems with hypothalamus-pituitary-endocrine gland feedback system causes disease; increased insulin growth factor increases aging.
(which theory)
Non stochastic biological theory
Fault immunological function causes induces aging
Non stochastic biological theory
Disengagement psychosocial
Gradual withdrawal from society and relationships serves to maintain social equilibrium and promote internal reflection (Sociological Theory)
Gerotranscendence:
Sociological theory
Elderly transform from a materialistic/rational perspective toward oneness with the universe.
Theory of thriving
Failure to thrive results from a discord between the individual and their environment/relationships.
To improve patients well-being, nurses strive to identify and modify factors that contribute to disharmony among these elements. (Nursing Theory)
Integumentary common changes in older adults
loss of skin elasticity with fat loss in extremities
pigmentation changes
glandular atrophy (oil, moisture, sweat glands)
thinning hair
slower nail growth
Respiratory changes in aging
decreased cough reflex
decreased cilia
increased anterior-posterior chest diameter
increased chest wall rigidity
fewer alveoli
increased airway resistance
increased risk of respiratory infections
Immune system changes in aging
thymus decreases in size and volume
t-cell function decreases
core temp elevation is lowered
Cognitive appropriate teaching methods
Discussion (one on one group)
Lecture
Question-answer session
Role play, discovery
Independent project
Affective appropriate teaching methods
role play
discussion group
discussion (one on one)
Psychomotor appropriate teaching methods
demonstration
practice
return demonstration
independent project, games
Cognitive learning encompasses
thinking and the acquisition of knowledge and intellectual skills
Affective learning deals
with the expression of feelings and development of values, attitudes and beliefs
Psychomotor learning involves
acquiring motor skills that require coordination and the integration of mental and physical movements such as the ability to walk or use an eating utensil
Teaching method for infant
keep routines consistent
hold infant firmly while smiling and speaking softly to convey sense of trust
Have infant touch different textures
Teaching method for toddler
use play to teach procedure or activity
offer picture books that describe story of children in hospital or clinic
use simple words
Teaching method for preschooler
use role play, imitation and play to make learning fun
encourage questions and offer explanations
encourage children to learn together through pictures and short stories about how to perform hygiene
School-age child teaching method
teach psychomotor skills needed to maintain health
offer opportunities to discuss health problems and answer questions
Adolescent teaching method
Help adolescent learn about feelings and need for self-expression
use teaching as collaborative activity
allow adolescents to make decisions about health and health promotion (safety, sex education, substance abuse)
PROBLEM SOLVING
Young/middle adult teaching methods
participation in teaching plan by setting mutual goals
independent learning
offer info so adult understands effects of health problem
Older adult teaching methods
teach when patient is alert and rested
involve adult in discussion or activity
focus on wellness and person’s strength
short teaching sessions
Immobility causes the release of _____ into circulation which can turn into
calcium
hypercalcemia
Suprainfection
develops when broad spectrum antibiotics eliminate a wide range of normal flora organisms, not just those causing infection
when normal bacterial floras are eliminated, body defenses are reduced, which allows disease producing microorganisms to multiply, causing illness
5 signs of inflammation
swelling
redness
heat
pain/tenderness
loss of function in affected body part
Major sites for HAI
surgical or traumatic wounds
urinary tract
respiratory tract
bloodstream
Mind-body interventions
biofeedback
breathwork
guided imagery
meditation
music therapy
tai chi
yoga
stress response physiological changes
increased heart/respiratory rate
tightened muscles
increased metabolic rate
general sense of forebonding
fear
nervousness
irritability
negative mood
elevated blood pressure
dilated pupils
stronger cardiac contractions
increased blood glucose, cholesterol, free fatty acids and triglycerides
research shows relaxation techniques effectively
lower blood pressure and heart rate
decrease muscle tension
improve well-being
reduce symptom distress in people experiencing a variety of situations
reduction of hypertension, depression
Aloe vera effects
acceleration of wound healing
chamomile effects
anti-inflammatory
calming agent
echinacea effects
stimulant of immune system
feverfew effects
anti-inflammatory
inhibitions serotonin and prostaglandins
garlic effects
inhibitions platelet aggregation
ginger effect
antiemetic
gingko biloba effect
memory improvement
ginseng effect
increased physical endurance,
improved immune function