53. Mannitol Flashcards Preview

Renal > 53. Mannitol > Flashcards

Flashcards in 53. Mannitol Deck (6):
1

MECHANISM

Osmotic diuretic. Increased tubular fluid osmolarity
--> increased urine flow, decreased intracranial/intraocular
pressure.

2

clinical use

Drug overdose, elevated intracranial/intraocular
pressure

3

Adverse effects

Pulmonary edema, dehydration.

4

Contraindicated in

anuria, HF.

5

• A patient takes a diuretic for increased intracranial pressure. What is the drug and its mechanism of action?

Mannitol, an osmotic diuretic, which increases tubular fluid osmolarity and therefore urine flow rate (also acts on intraocular pressure)

6

• A patient with anuria presents with heart failure. Is it safe to give this patient an osmotic diuretic?

No (osmotic diuretics such as mannitol are contraindicated in patients with anuria and/or heart failure)

Decks in Renal Class (61):