Flashcards in 53. Mannitol Deck (6):
Osmotic diuretic. Increased tubular fluid osmolarity
--> increased urine flow, decreased intracranial/intraocular
Drug overdose, elevated intracranial/intraocular
Pulmonary edema, dehydration.
• A patient takes a diuretic for increased intracranial pressure. What is the drug and its mechanism of action?
Mannitol, an osmotic diuretic, which increases tubular fluid osmolarity and therefore urine flow rate (also acts on intraocular pressure)