54. Acetazolamide Flashcards Preview

Renal > 54. Acetazolamide > Flashcards

Flashcards in 54. Acetazolamide Deck (6):
1

MECHANISM

Carbonic anhydrase inhibitor. Causes selflimited
NaHCO3 diuresis and  total body
HCO3
− stores

2

CLINICAL USE

Glaucoma, urinary alkalinization, metabolic
alkalosis, altitude sickness, pseudotumor
cerebri.

3

ADVERSE EFFECTS

Proximal renal tubular acidosis, paresthesias,
NH3 toxicity, sulfa allergy.

4

• A patient starts taking acetazolamide for mild altitude sickness. What is the mechanism of action of this drug?

It acts as a carbonic anhydrase inhibitor, causing self-limited sodium bicarbonate diuresis and a reduction in total-body bicarbonate stores

5

• Name some clinical indications for acetazolamide.

Glaucoma, urinary alkalinization, metabolic alkalosis, altitude sickness, pseudotumor cerebri

6

• Name some clinical indications for acetazolamide.

Glaucoma, urinary alkalinization, metabolic alkalosis, altitude sickness, pseudotumor cerebri

Decks in Renal Class (61):