Flashcards in 59. Non-alcoholic fatty liver disease Deck (7)
non - alcoholic syndrome - alcohol use ? ALT vs AST ?
ALT > AST
Non - alcoholic syndrome is associated with .... ---> mechanism
metabolic syndrome ( insulin resistance)
obesity --> fatty infiltration of hepatocytes --> cellular " balloning" and ebentual necrosis
non - alcoholic syndromemay cause
Cirrhosis and HCC
• What is the AST:ALT ratio in non-alcoholic fatty liver disease?
ALT > AST (ALT = Lipids)
• A non-alcoholic, type II diabetic patient has cirrhosis and a high ALT:AST ratio. What pathologic changes are associated with this disease?
Insulin resistance = fatty infiltration of hepatocytes & cellular ballooning on pathology (as seen in non-alcoholic fatty liver disease)
• What type of syndrome is associated with non-alcoholic fatty liver disease?
Metabolic syndrome (insulin resistance)