59. Non-alcoholic fatty liver disease Flashcards Preview

Gastrointestinal > 59. Non-alcoholic fatty liver disease > Flashcards

Flashcards in 59. Non-alcoholic fatty liver disease Deck (7)
1

non - alcoholic syndrome - alcohol use ? ALT vs AST ?

independent
ALT > AST

2

Non - alcoholic syndrome is associated with .... ---> mechanism

metabolic syndrome ( insulin resistance)
obesity --> fatty infiltration of hepatocytes --> cellular " balloning" and ebentual necrosis

3

non - alcoholic syndromemay cause

Cirrhosis and HCC

4

• What is the AST:ALT ratio in non-alcoholic fatty liver disease?

ALT > AST (ALT = Lipids)

5

• A non-alcoholic, type II diabetic patient has cirrhosis and a high ALT:AST ratio. What pathologic changes are associated with this disease?

Insulin resistance = fatty infiltration of hepatocytes & cellular ballooning on pathology (as seen in non-alcoholic fatty liver disease)

6

• What type of syndrome is associated with non-alcoholic fatty liver disease?

Metabolic syndrome (insulin resistance)

7

• A non-alcoholic man with a high ALT:AST ratio and metabolic syndrome should be advised that he is at risk for what type(s) of liver disease?

Cirrhosis and HCC (he has non-alcoholic fatty liver disease)

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