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Flashcards in 6. Clinical Micro NAT Deck (3)
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1

What can upregulate the expression of mecA/mecC?

When SSCmec-containing bacteria is exposed to B-lactam antibiotics

2

Peptide cross-linking enzymatic domain of PBP2

Transpeptidase

3

What do B-lactam antibiotics bind to (mechanism of action)?

PBP2 transpeptidase domain = inactivates bacterial wall cross-linking during growth