7.5 Agents of Viral Gastrointestinal Infections Flashcards Preview

Microbiology > 7.5 Agents of Viral Gastrointestinal Infections > Flashcards

Flashcards in 7.5 Agents of Viral Gastrointestinal Infections Deck (16)
Loading flashcards...
1

Most common cause of viral disease

Rotavirus

2

Rotavirus group that is primary human pathogens

Group A

3

2 concentric capsid shells with icosahedral symmetry
Non-enveloped, double shelled

Rotavirus

4

Rotavirus is inactivated by

95% enthanol, phenol, chloride and boiling water

5

Antigenic properties used to identify rotavirus

Inner unit: VP6
Outer unit: VP4 (P serotype) and VP7 (G serotype)

6

Released by rotavirus that induces electrolyte imbalance by triggering a signal transduction pathway

NSP4 enterotoxin

7

Rotavirus replication in the ____ followed by acute onset of vomiting and diarrhea

Small intestine

8

Common source of infection in adults is ____

Contact with pediatric cases

9

Rotavirus epidemiology: most common cause of _____ in _____; prominent during the ____; inactivated by ____

Gastroenteritis
Children
Winter season
Alcohol

10

Oral rhesus vaccine is withdrawn a year later because of reports of ____

Intussusception

11

Norwalk virus family

Caliciviridae (4 genera - Sapovirus, Lagovirus, Vesivirus, Novovirus)

12

Cup-like depressions on the surface of the virus with icosahedral symmetery; single-stranded RNA and contain single structural protein

Norwalk virus

13

Norwalk virus is maintained in iced and partially cooked ____., eliminated by ____

Oysters
Chloride-based disinfectants

14

Most important cause of epidemic viral gastroenteritis

Norwalk virus

15

Rapid onset of diarrhea, N/V, low-grade fever, abdominal cramps, headache, and malaise

Norwalk virus gastroenteritis

16

Most widely used technique for detection of human caliciviruses in clinical specimens

RT-PCR