Flashcards in 7.5 Agents of Viral Gastrointestinal Infections Deck (16)
Loading flashcards...
1
Most common cause of viral disease
Rotavirus
2
Rotavirus group that is primary human pathogens
Group A
3
2 concentric capsid shells with icosahedral symmetry
Non-enveloped, double shelled
Rotavirus
4
Rotavirus is inactivated by
95% enthanol, phenol, chloride and boiling water
5
Antigenic properties used to identify rotavirus
Inner unit: VP6
Outer unit: VP4 (P serotype) and VP7 (G serotype)
6
Released by rotavirus that induces electrolyte imbalance by triggering a signal transduction pathway
NSP4 enterotoxin
7
Rotavirus replication in the ____ followed by acute onset of vomiting and diarrhea
Small intestine
8
Common source of infection in adults is ____
Contact with pediatric cases
9
Rotavirus epidemiology: most common cause of _____ in _____; prominent during the ____; inactivated by ____
Gastroenteritis
Children
Winter season
Alcohol
10
Oral rhesus vaccine is withdrawn a year later because of reports of ____
Intussusception
11
Norwalk virus family
Caliciviridae (4 genera - Sapovirus, Lagovirus, Vesivirus, Novovirus)
12
Cup-like depressions on the surface of the virus with icosahedral symmetery; single-stranded RNA and contain single structural protein
Norwalk virus
13
Norwalk virus is maintained in iced and partially cooked ____., eliminated by ____
Oysters
Chloride-based disinfectants
14
Most important cause of epidemic viral gastroenteritis
Norwalk virus
15
Rapid onset of diarrhea, N/V, low-grade fever, abdominal cramps, headache, and malaise
Norwalk virus gastroenteritis
16
