Flashcards in 8. Fluid compartments Deck (24):

1

## Total body water ( TBW ) - proportion

### 60% of body mass

2

## Non water mass ( NWM) - proportion

### 40% body mass

3

## total body water mass and non water mass if Body mass is 70 Kg

###
-total body water --> 60 % of body mass= 42 kg = 42 L

-non water mass--> 40% of body mass = 28kg

4

## Total body water ( TBW) is divided to ... ( and proprotions)

###
1. extracellular fluid ( ECF) --> 1/3

2. intracellular fluid ( ICF) --> 2/3

5

## extracellular fluid (ECF) in a body mass 70 kg

### 1/3 of 60% body mass --> 20 % of body mass--> 14 kg ---> 14L

6

## intracellular fluid ( iCF) in body mass 70 kg

### 2/3 of 60% body mass --> 40 % of body mass --> 28kg --> 28L

7

## extracellular fluid ( ECF) vs intracellular fluid ( ICF) according to proportion in body mass

###
extracellular fluid ( ECF) --> 20%

intracellular fluid (ICF) --> 40%

8

## extracellular fluid ( ECF) is divided to ( proportions and L in body mass 70 kg)

###
1. interstitial fluid --> 75% ECF -->10.5 L

2. plasma --> 25% ECF --> 3.5 kg ---> 3.5 L

9

## RBC volume

### 2.8L ( PART OF intracellular fluid)

10

## blood constist of ( and volumes )

### RBCs (2.8L ) and plasma (3.5L) -->6.2L

11

## Normal HCT ( calculation and alternative calculation)

###
RBC volume / blood volume = 2.8 / 6.2 = 45%

alternatively --> HCT (%) = 3X(Hb) in g/dL

12

## Plasma volume can be measured by

### radiolabelling albumin or Evans blue ( it binds albumin )

13

## Extracellular volume can be measured by

### inulin or manitol, sulfate

14

## osmolarity is the

### measure of solute concentration, defined as the number of osmoles ( Osm ) of solute per litre (L) of solution

15

## osmolarity - normal range

### 285-295 mOsm/ kg H2O

16

## Nonwater mass accounts for ____% of total body weight, or ____ kg in a person weighing 70 kg.

### 40%; 28 kg

17

## What fraction of total body water is extracellular vs. intracellular? What fraction of extracellular fluid is plasma vs. interstitial?

### Total body water = one third extracellular, two thirds intracellular; of extracellular fluid = one fourth plasma, three fourths interstitial

18

## In an experiment, radiolabeled albumin and, later, radiolabeled inulin are infused into a patient. What two variables are being measured?

### Radiolabeled albumin may be used to measure plasma volume, and inulin may be used to measure extracellular volume

19

## • What is the 60-40-20 rule of (percentage of body weight) for the average person?

### 60% of total body weight is total body water, 40% is intracellular fluid (ICF), and 20% is extracellular fluid (ECF)

20

## A healthy patient's plasma osmolarity is measured during a routine visit. It is found to be normal. What value do you expect to see?

### 285–295 mOsm/kg

21

## • Of the extracellular fluid, what percentage is interstitial fluid, and what percentage is plasma?

### 75; 25%

22

## • Of the extracellular fluid in a 70-kg man, what volume and mass is the interstitial fluid, and what volume and mass is the plasma?

### 10.5 L and 10.5 kg; 3.5 L and 3.5 kg

23

## • What is the volume of water contained within RBCs in the intracellular fluid of a 70-kg man?

### 2.8 L

24