Flashcards in 81. Octreotide Deck (6)
Octreotide - mechanism
Long-acting somatostatin analog; inhibits secretion of various splanchnic vasodilatory hormones
Octreotide - clinical use
Acute variceal bleeds, acromegaly, VIPoma, carcinoid tumors.
Octreotide - adverse effects
Nausea, cramps, steatorrhea. Increased risk of cholelithiasis due to CCK inhibition
• A patient presents with bleeding esophageal varices. What is the mechanism of action of a drug that can acutely help abort the bleeding?
Octreotide is a long-acting somatostatin analog that inhibits actions of many splanchnic vasoconstriction hormones
• A patient on pharmacologic treatment for a VIPoma experiences nausea, cramps, and steatorrhea. What medication is she likely taking?