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Flashcards in 9 Problem drugs in elderly Deck (15):
1

Diuretics esp. bendro
4

hyponatraemia
dehydration
renal impairment
postural hypotension

2

Antihypertensives
e.g. short acting nifedipine
4

dehydration
renal impairment
postural hypotension
beta-blockers less effectibve due to loss or recptor sensitivity

3

CNS acting agents
esp. TCAs, fluoxetine, long acting BZs (diazepam)
3

postural sway
confusion
falls
(due to increased sensitivity of the CNS to all drugs)

4

Opioids
2

hypotension
constipation
CNS effects

5

NSAIDs
3

fluid retension
GI and renal tox

6

Anticholinergics
e.g. TCA, oxybutanin
4

blurred vision
constipation
confusion
urinary retention

7

long term hypoglycaemics
e.g. glibencamide
1

increased risk of hypos

8

Warfarin
2

Increases sensitivity
increased risk from falls
WARFARIN DOES NOT CAUSE FALLS

9

Digoxin
1

increased risk of tox
no more than 125microg dose

10

Drugs for PD
1

More pronounced s/e

11

Key parameters to measure

Haematology
1. FBC
Biochemistry
2. LFTs
3. U&Es
4. Blood sugar
5. TFTs
6. Blood lipids

7. Body mass index or equivalent
8. Drug therapeutic target ranges

12

Signs of hyponatraemia 3

muscle cramps
slurred speech
confusion

13

signs of hypoglycaemia 8

nausea
cold sweat
weakness
fainting
confusion
headache
bizarre behaviour

14

signs of anaemia 4

tiredness
palpitations
SOB
dizziness

15

signs of hypokalaemia

muscle weakness
intestinal atony (loss of strength)
increased sensitivity to dig
polyuria
poyldypsia